Simons Laura E, Smith Allison, Ibagon Camila, Coakley Rachael, Logan Deirdre E, Schechter Neil, Borsook David, Hill Jonathan C
Division of Pain Medicine, Department of Anesthesiology, Perioperative and Pain Medicine, Boston Children's Hospital, Boston, MA, USA Department of Psychiatry, Harvard Medical School, Boston, MA, USA PAIN Group, Boston Children's Hospital and Center for Pain and the Brain, Boston, MA, USA Arthritis Research UK Primary Care Centre, Keele University, United Kingdom.
Pain. 2015 Aug;156(8):1511-1518. doi: 10.1097/j.pain.0000000000000199.
Moderate to severe chronic pain is a problem for 1.7 million children, costing $19.5 billion dollars annually in the United States alone. Risk-stratified care is known to improve outcomes in adults with chronic pain. However, no tool exists to stratify youth who present with pain complaints to appropriate interventions. The Pediatric Pain Screening Tool (PPST) presented here assesses prognostic factors associated with adverse outcomes among youth and defines risk groups to inform efficient treatment decision making. Youth (n = 321, ages 8-18, 90.0% Caucasian, 74.8% female) presenting for multidisciplinary pain clinic evaluation at a tertiary care center participated. Of these, 195 (61.1%) participated at 4-month follow-up. Participants completed the 9-item PPST in addition to measures of functional disability, pain catastrophizing, fear of pain, anxiety, and depressive symptoms. Sensitivity and specificity for the PPST ranged from adequate to excellent, with regard to significant disability (78%, 68%) and high emotional distress (81%, 63%). Participants were classified into low- (11%), medium- (32%), and high- (57%) risk groups. Risk groups did not significantly differ by pain diagnosis, location, or duration. Only 2% to 7% of patients who met reference standard case status for disability and emotional distress at 4-month follow-up were classified as low risk at baseline, whereas 71% to 79% of patients who met reference standard case status at follow-up were classified as high risk at baseline. A 9-item screening tool identifying factors associated with adverse outcomes among youth who present with pain complaints seems valid and provides risk stratification that can potentially guide effective pain treatment recommendations in the clinic setting.
在美国,170万儿童面临中度至重度慢性疼痛问题,仅美国每年为此花费195亿美元。已知风险分层护理可改善慢性疼痛成人患者的治疗效果。然而,目前尚无工具可对有疼痛主诉的青少年进行分层,以采取适当干预措施。本文介绍的儿童疼痛筛查工具(PPST)评估了与青少年不良结局相关的预后因素,并定义了风险组,以指导有效的治疗决策。在一家三级护理中心接受多学科疼痛门诊评估的青少年(n = 321,年龄8 - 18岁,90.0%为白种人,74.8%为女性)参与了研究。其中,195名(61.1%)参与了4个月的随访。参与者除完成9项PPST外,还进行了功能残疾、疼痛灾难化、疼痛恐惧、焦虑和抑郁症状的测量。PPST对于显著残疾(78%,68%)和高度情绪困扰(81%,63%)的敏感性和特异性从足够到优秀不等。参与者被分为低风险组(11%)、中风险组(32%)和高风险组(57%)。风险组在疼痛诊断、部位或持续时间方面无显著差异。在4个月随访时符合残疾和情绪困扰参考标准病例状态的患者中,只有2%至7%在基线时被分类为低风险,而在随访时符合参考标准病例状态的患者中,71%至79%在基线时被分类为高风险。一种识别有疼痛主诉青少年不良结局相关因素的9项筛查工具似乎有效,并提供了风险分层,有可能在临床环境中指导有效的疼痛治疗建议。