佐帕特尔。十一。绒毛山菊和灌木山菊对大鼠子宫条的作用。

The zoapatle. XI. Effects elicited by Montanoa tomentosa and Montanoa frutescens on rat uterine strips.

作者信息

Perusquía M, Sánchez E, Ponce-Monter H, Estrada A V, Pedrón N, Valencia A, Guzmán A, Gallegos A J

出版信息

Contraception. 1985 May;31(5):543-51. doi: 10.1016/0010-7824(85)90089-7.

Abstract

Zoapatle aqueous crude extract (ZACE) obtained from Montanoa tomentosa (M.t.) inhibits the in vitro spontaneous contractility pattern of rat uterine tissue. The opposite effect was observed with ZACE from Montanoa frutescens (M.f.) in the same preparation. Both plant extracts, M.t. and M.f., increased the in vitro spontaneous contractility pattern in the uterine guinea pig assay. In depolarized uterine tissue, propranolol (beta-blocker) inhibited the relaxing effect induced by M.t.. Atropine (cholinergic antagonist) abolished the increase in uterus contractility produced by the presence of M.f.

摘要

从绒毛山菊（Montanoa tomentosa，M.t.）中提取的佐帕特尔水粗提物（Zoapatle aqueous crude extract，ZACE）可抑制大鼠子宫组织的体外自发收缩模式。在相同制剂中，来自弗鲁特山菊（Montanoa frutescens，M.f.）的ZACE则观察到相反的效果。M.t.和M.f.这两种植物提取物在豚鼠子宫试验中均增加了体外自发收缩模式。在去极化的子宫组织中，普萘洛尔（β受体阻滞剂）抑制了M.t.诱导的舒张作用。阿托品（胆碱能拮抗剂）消除了M.f.存在时子宫收缩力的增加。