墨西哥泽漆V——贝壳杉二烯酸对子宫收缩性的影响。

The zoapatle V--the effect of kauradienoic acid upon uterine contractility.

作者信息

Lozoya X, Enríquez R G, Bejar E, Estrada A V, Girón H, Ponce-Monter H, Gallegos A J

出版信息

Contraception. 1983 Mar;27(3):267-79. doi: 10.1016/0010-7824(83)90005-7.

Abstract

Kauradienoic acid was obtained from the hexanic extract of M. tomentosa (Cerv) leaves by chromatographic separation. This substance influenced the in vitro contractility of the rat, dog and guinea pig uterine strips. It also induced strong contractions of the guinea pig uterus in vivo when administered intravenously, without changes on arterial blood pressure. The effects produced by the plant infusion, the hexanic extract and pure species were compared. The hexanic of other utero-active compounds in M. tomentosa in addition to those already described is discussed.

摘要

从绒毛番荔枝（M. tomentosa (Cerv)）叶的己烷提取物中通过色谱分离得到了考来二烯酸。该物质影响大鼠、犬和豚鼠子宫条的体外收缩性。静脉注射时，它还能在体内引起豚鼠子宫强烈收缩，且对动脉血压无影响。比较了植物浸剂、己烷提取物和纯物质产生的效果。还讨论了绒毛番荔枝中除已描述的那些之外的其他子宫活性化合物的己烷提取物。