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Do Adult Somatic Cells Undergo Reprogramming or Endogenous Pluripotent Stem Cells get Activated to Account for Plasticity, Regeneration and Cancer Initiation?

作者信息

Bhartiya Deepa

机构信息

Stem Cell Biology Department, National Institute for Research in Reproductive Health (Indian Council of Medical Research), Jehangir Merwanji Street, Parel, Mumbai, 400 012, India.

出版信息

Stem Cell Rev Rep. 2017 Oct;13(5):699-701. doi: 10.1007/s12015-017-9749-x.

DOI:10.1007/s12015-017-9749-x
PMID:28631014
Abstract
摘要

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Mouse Bone Marrow VSELs Exhibit Differentiation into Three Embryonic Germ Lineages and Germ & Hematopoietic Cells in Culture.小鼠骨髓 VSELs 在培养中表现出向三种胚胎生殖系和生殖与造血细胞的分化。
Stem Cell Rev Rep. 2017 Apr;13(2):202-216. doi: 10.1007/s12015-016-9714-0.
2
A Novel View of the Adult Stem Cell Compartment From the Perspective of a Quiescent Population of Very Small Embryonic-Like Stem Cells.从非常小的胚胎样干细胞静止群体的角度看成人干细胞区室的新观点。
Circ Res. 2017 Jan 6;120(1):166-178. doi: 10.1161/CIRCRESAHA.116.309362.
3
Endogenous, very small embryonic-like stem cells: critical review, therapeutic potential and a look ahead.
低硬度基质可增强真皮成纤维细胞的表观遗传擦除和向胰岛素分泌细胞的分化。
Stem Cell Rev Rep. 2018 Jun;14(3):398-411. doi: 10.1007/s12015-017-9799-0.
4
Stem Cells and Progenitors in Human Peripheral Blood Get Activated by Extremely Active Resveratrol (XAR™).人外周血中的干细胞和祖细胞被超强活性白藜芦醇(XAR)激活。
Stem Cell Rev Rep. 2018 Apr;14(2):213-222. doi: 10.1007/s12015-017-9784-7.
5
Shifting gears from embryonic to very small embryonic-like stem cells for regenerative medicine.从胚胎干细胞转向非常小的类胚胎干细胞用于再生医学。
Indian J Med Res. 2017 Jul;146(1):15-21. doi: 10.4103/ijmr.IJMR_1485_16.
6
Pluripotent Stem Cells in Adult Tissues: Struggling To Be Acknowledged Over Two Decades.成体组织中的多能干细胞:历经二十余年,努力寻求认可。
Stem Cell Rev Rep. 2017 Dec;13(6):713-724. doi: 10.1007/s12015-017-9756-y.
内源性,非常小的胚胎样干细胞:关键评论、治疗潜力和展望。
Hum Reprod Update. 2016 Dec;23(1):41-76. doi: 10.1093/humupd/dmw030. Epub 2016 Sep 10.
4
Very small embryonic-like stem cells are involved in regeneration of mouse pancreas post-pancreatectomy.非常小的胚胎样干细胞参与小鼠胰腺切除术后的胰腺再生。
Stem Cell Res Ther. 2014 Sep 2;5(5):106. doi: 10.1186/scrt494.
5
Multilineage-differentiating stress-enduring (Muse) cells are a primary source of induced pluripotent stem cells in human fibroblasts.多能性分化应激耐受(Muse)细胞是人成纤维细胞诱导多能干细胞的主要来源。
Proc Natl Acad Sci U S A. 2011 Jun 14;108(24):9875-80. doi: 10.1073/pnas.1100816108. Epub 2011 May 31.
6
Epiblast/germ line hypothesis of cancer development revisited: lesson from the presence of Oct-4+ cells in adult tissues.重新审视癌症发生的外胚层/生殖细胞假说:来自成年组织中存在 Oct-4+细胞的启示。
Stem Cell Rev Rep. 2010 Jun;6(2):307-16. doi: 10.1007/s12015-010-9143-4.