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成釉细胞瘤:对果阿人群的一项为期16年的临床病理研究。

Ameloblastoma: A 16-year clinicopathological study on Goan population.

作者信息

Carvalho Karla Maria, Dhupar Anita, Spadigam Anita, Syed Shaheen

机构信息

Department of Oral and Maxillofacial Pathology, Goa Dental College and Hospital, Bambolim, Goa, India.

出版信息

Indian J Pathol Microbiol. 2017 Apr-Jun;60(2):157-160. doi: 10.4103/0377-4929.208374.

Abstract

BACKGROUND

Ameloblastoma is a benign slow growing tumor of odontogenic origin composed of epithelial cells that resemble enamel forming cells namely the ameloblasts however these lesional cells do not differentiate to produce enamel. They are locally aggressive and can cause severe abnormalities of the face and jaw.

AIM

This study aimed to correlate the incidence and recurrence rates of ameloblastoma to the different clinical and histopathological parameters.

METHODS

A study on ameloblastomas in the Goan population for 16 years (1999-2014) was carried out. Archived documented data of surgically treated cases of ameloblastomas were used in this study.

RESULTS

It was revealed that out of 52 cases of ameloblastomas, a male preponderance was seen. Age predisposition was seen to favor the third-fourth decade, the most common site was the posterior aspect of lower jaw for new and recurrent cases.

CONCLUSION

The study highlights, the possible etiological role of location influencing the incidence and recurrence rates of ameloblastomas.

摘要

背景

成釉细胞瘤是一种起源于牙源性的良性、生长缓慢的肿瘤,由类似于成釉细胞(即形成牙釉质的细胞)的上皮细胞组成,然而这些病变细胞不会分化产生牙釉质。它们具有局部侵袭性,可导致面部和颌骨的严重畸形。

目的

本研究旨在将成釉细胞瘤的发病率和复发率与不同的临床和组织病理学参数相关联。

方法

对果阿人群中的成釉细胞瘤进行了为期16年(1999 - 2014年)的研究。本研究使用了手术治疗的成釉细胞瘤病例的存档记录数据。

结果

结果显示,在52例成釉细胞瘤病例中,男性居多。年龄倾向于第三至第四个十年,新发病例和复发病例最常见的部位是下颌后部。

结论

该研究强调了位置可能对成釉细胞瘤的发病率和复发率产生病因学影响。

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