Wu P C, Chan K W
Br J Oral Maxillofac Surg. 1985 Apr;23(2):92-102. doi: 10.1016/0266-4356(85)90058-0.
A total of 114 tumours of the jawbones was confirmed in a survey of 204,583 surgical specimens in Chinese in the University Department of Pathology, Hong Kong from 1963-1982. Odontogenic tumours totalled 82 of which 62 per cent were ameloblastomas. Thus, odontogenic tumours, in particular ameloblastomas, are relatively common in Chinese. In the 51 cases of ameloblastoma, the mean age at presentation in females was significantly younger than in males. Pathological analysis of the ameloblastomas showed the following: (1) connection of tumour epithelium with oral mucosal epithelium suggests a better prognosis; (2) basaloid pattern in the tumour may prognostically indicate a more aggressive biological behaviour; (3) neoplastic infiltration of the grossly normal bone surrounding the tumour mass was frequent; (4) ameloblastomas not uncommonly contained cysts lined by innocuous-looking epithelium; (5) a significant proportion of ameloblastomas appeared grossly as thin-walled unilocular cysts. The implications of these findings in the diagnosis and treatment of ameloblastoma are emphasized.
1963年至1982年期间，香港大学病理系对204,583份中文手术标本进行了调查，共确诊114例颌骨肿瘤。牙源性肿瘤共计82例，其中62%为成釉细胞瘤。因此，牙源性肿瘤，尤其是成釉细胞瘤，在中国人群中相对常见。在51例成釉细胞瘤病例中，女性患者的平均发病年龄明显低于男性。对成釉细胞瘤的病理分析显示如下：（1）肿瘤上皮与口腔黏膜上皮相连提示预后较好；（2）肿瘤中的基底样模式在预后上可能提示更具侵袭性的生物学行为；（3）肿瘤块周围大体正常骨的肿瘤性浸润很常见；（4）成釉细胞瘤中常含有由看似无害的上皮衬里的囊肿；（5）相当一部分成釉细胞瘤大体上表现为薄壁单房囊肿。文中强调了这些发现对成釉细胞瘤诊断和治疗的意义。
