聚阳离子配体阳离子化铁蛋白对量子递质释放的抑制作用。
Inhibition of quantal transmitter release by the polycationic ligand cationized ferritin.
作者信息
Publicover S J
出版信息
Exp Brain Res. 1985;59(3):629-32. doi: 10.1007/BF00261355.
PMID:2863166
Abstract
Cationized ferritin (200 micrograms ml-1) causes a reduction in both spontaneous and evoked transmitter release at the frog neuromuscular junction. The reduction in EPP amplitude probably reflects reduced Ca2+ -influx since full recovery can be achieved by elevation of [Ca2+]o. The effect on MEPP frequency is independent of [Ca2+]o and may well reflect a direct effect on exocytosis.
摘要
阳离子铁蛋白（200微克/毫升）可使青蛙神经肌肉接头处的自发递质释放和诱发递质释放均减少。终板电位（EPP）幅度的降低可能反映了Ca2+内流的减少，因为通过提高细胞外Ca2+浓度（[Ca2+]o）可实现完全恢复。对微小终板电位（MEPP）频率的影响与[Ca2+]o无关，很可能反映了对胞吐作用的直接影响。
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