Sch 34343与其他抗菌剂对厌氧菌的体外活性比较
Comparative in-vitro activity of Sch 34343 and other antimicrobial agents against anaerobic bacteria.
作者信息
Nord C E, Olsson-Liljequist B
出版信息
J Antimicrob Chemother. 1985 Jun;15 Suppl C:183-8. doi: 10.1093/jac/15.suppl_c.183.
The activity of Sch 34343 was determined against 575 strains of anaerobic bacteria by an agar-dilution method. Its activity was compared with that of benzylpenicillin, piperacillin, cefoxitin, imipenem, clindamycin, metronidazole, chloramphenicol, vancomycin, fusidic acid and bacitracin. Sch 34343 and imipenem were the most active agents tested. Based on these results, Sch 34343 appears to be a promising antimicrobial agent for anaerobic infections and warrants further clinical investigations.
采用琼脂稀释法测定了Sch 34343对575株厌氧菌的活性。将其活性与苄青霉素、哌拉西林、头孢西丁、亚胺培南、克林霉素、甲硝唑、氯霉素、万古霉素、夫西地酸和杆菌肽进行了比较。Sch 34343和亚胺培南是测试的最具活性的药物。基于这些结果，Sch 34343似乎是一种有前景的用于厌氧菌感染的抗菌药物，值得进一步进行临床研究。
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