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培养基、pH值和接种量对头孢唑肟和Sch-34343抗厌氧菌活性的影响。

Effect of medium, pH, and inoculum size on activity of ceftizoxime and Sch-34343 against anaerobic bacteria.

作者信息

Borobio M V, Pascual A, Dominguez M C, Perea E J

出版信息

Antimicrob Agents Chemother. 1986 Oct;30(4):626-7. doi: 10.1128/AAC.30.4.626.

DOI:10.1128/AAC.30.4.626
PMID:3466569
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC176497/
Abstract

The effect of two media, three pH values, and three inoculum densities on the activity of ceftizoxime and Sch-34343 against anaerobic bacteria was evaluated. The activities of both antimicrobial agents were affected by medium composition, especially against Bacteroides fragilis. Changes in pH and inoculum size affected only the activity of ceftizoxime against anaerobic bacteria.

摘要

评估了两种培养基、三种pH值和三种接种密度对头孢唑肟和Sch-34343抗厌氧菌活性的影响。两种抗菌剂的活性均受培养基成分影响，尤其是对脆弱拟杆菌。pH值和接种量的变化仅影响头孢唑肟对厌氧菌的活性。

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本文引用的文献

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Comparative in vitro activity of new beta-lactam antibiotics against anaerobic bacteria.新型β-内酰胺类抗生素对厌氧菌的体外活性比较
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Antibacterial activity of ceftizoxime, a beta-lactamase-stable cephalosporin.头孢唑肟（一种对β-内酰胺酶稳定的头孢菌素）的抗菌活性
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N-formimidoyl-thienamycin activity against anaerobes: effect of the inoculum, pH and culture media.N-甲酰亚胺基硫霉素对厌氧菌的活性：接种量、pH值和培养基的影响
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Comparison of the activities of penicillin G and new beta-lactam antibiotics against clinical isolates of Bacteroides species.青霉素G与新型β-内酰胺类抗生素对拟杆菌属临床分离株的活性比较。
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In-vitro activity of ceftizoxime against anaerobic bacteria and comparison with other cephalosporins.头孢唑肟对厌氧菌的体外活性及其与其他头孢菌素的比较。
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Comparative in vitro activity of ceftizoxime, cefoperazone, and cefoxitin against anaerobic bacteria.头孢唑肟、头孢哌酮和头孢西丁对厌氧菌的体外活性比较
Antimicrob Agents Chemother. 1981 Nov;20(5):683-5. doi: 10.1128/AAC.20.5.683.
7
In vitro activity of ceftizoxime against Bacteroides fragilis: comparison with benzylpenicillin, cephalothin, and cefoxitin.头孢唑肟对脆弱拟杆菌的体外活性：与苄青霉素、头孢噻吩和头孢西丁的比较。
Antimicrob Agents Chemother. 1981 Sep;20(3):332-5. doi: 10.1128/AAC.20.3.332.
8
Comparative in vitro activities of cefotaxime and ceftizoxime (FK749): new cephalosporins with exceptional potency.头孢噻肟和头孢唑肟（FK749）的体外比较活性：具有卓越效力的新型头孢菌素。
Antimicrob Agents Chemother. 1980 Mar;17(3):397-401. doi: 10.1128/AAC.17.3.397.
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Novel method for detection of beta-lactamases by using a chromogenic cephalosporin substrate.一种使用显色头孢菌素底物检测β-内酰胺酶的新方法。
Antimicrob Agents Chemother. 1972 Apr;1(4):283-8. doi: 10.1128/AAC.1.4.283.
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Susceptibility of anaerobic bacteria to Sch 34343 and other antibiotics.
J Antimicrob Chemother. 1985 Jun;15 Suppl C:193-8. doi: 10.1093/jac/15.suppl_c.193.