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佐治亚州亚特兰大市男男性行为的黑人和白人使用暴露前预防措施的意愿。

Willingness to use pre-exposure prophylaxis among Black and White men who have sex with men in Atlanta, Georgia.

作者信息

Rolle Charlotte-Paige, Rosenberg Eli S, Luisi Nicole, Grey Jeremy, Sanchez Travis, Del Rio Carlos, Peterson John L, Frew Paula M, Sullivan Patrick S, Kelley Colleen F

机构信息

1 Division of Infectious Diseases, Emory University School of Medicine, Atlanta, GA, USA.

2 Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA, USA.

出版信息

Int J STD AIDS. 2017 Aug;28(9):849-857. doi: 10.1177/0956462416675095. Epub 2016 Oct 20.

Abstract

PrEP willingness may be different among black and white men who have sex with men (MSM) given known disparities in HIV incidence, sociodemographic factors, and healthcare access between these groups. We surveyed 482 black and white HIV-negative MSM in Atlanta, GA about their willingness to use pre-exposure prophylaxis (PrEP) and facilitators and barriers to PrEP willingness. Overall, 45% (215/482) of men indicated interest in using PrEP. Engaging in recent unprotected anal intercourse (UAI) was the only factor significantly associated with PrEP willingness in multivariate analyses (OR 1.73, 95% CI 1.13, 2.65). Willing men identified "extra protection" against HIV as the most common reason for interest in using PrEP, whereas unwilling men most commonly cited not wanting to take medication daily, and this reason was more common among white MSM (42.3% of white MSM vs. 28.9% of black MSM, p = 0.04). Most men indicated willingness to use PrEP if cost was <50 dollars/month; however, more black MSM indicated willingness to use PrEP only if cost were free (17.9% of white MSM vs. 25.9% of black MSM, p = 0.03). Overall, these data are useful to scale up PrEP interventions targeting at-risk MSM in Atlanta and highlight the need for implementation of low cost-programs, which will be especially important for black MSM.

摘要

鉴于男男性行为者(MSM)中黑人和白人在艾滋病病毒感染率、社会人口统计学因素以及医疗保健可及性方面存在已知差异,他们对暴露前预防(PrEP)的意愿可能有所不同。我们对佐治亚州亚特兰大市482名黑人和白人艾滋病病毒阴性的男男性行为者进行了调查,了解他们使用暴露前预防药物(PrEP)的意愿以及影响PrEP意愿的促进因素和障碍。总体而言,45%(215/482)的男性表示有兴趣使用PrEP。在多变量分析中,近期有未保护的肛交行为(UAI)是与PrEP意愿显著相关的唯一因素(比值比1.73,95%置信区间1.13,2.65)。愿意使用PrEP的男性将预防艾滋病病毒的“额外保护”视为对使用PrEP感兴趣的最常见原因,而不愿意使用的男性最常提到的是不想每天服药,并且这个原因在白人男男性行为者中更为常见(42.3%的白人男男性行为者 vs. 28.9%的黑人男男性行为者,p = 0.04)。大多数男性表示,如果每月费用低于50美元,他们愿意使用PrEP;然而,更多黑人男男性行为者表示仅在费用免费时才愿意使用PrEP(17.9%的白人男男性行为者 vs. 25.9%的黑人男男性行为者,p = 0.03)。总体而言,这些数据有助于扩大针对亚特兰大市高危男男性行为者的PrEP干预措施,并突出实施低成本项目的必要性,这对黑人男男性行为者尤为重要。

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