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关于三氯生和三氯卡班的佛罗伦萨声明。

The Florence Statement on Triclosan and Triclocarban.

作者信息

Halden Rolf U, Lindeman Avery E, Aiello Allison E, Andrews David, Arnold William A, Fair Patricia, Fuoco Rebecca E, Geer Laura A, Johnson Paula I, Lohmann Rainer, McNeill Kristopher, Sacks Victoria P, Schettler Ted, Weber Roland, Zoeller R Thomas, Blum Arlene

机构信息

Biodesign Center for Environmental Security, Arizona State University , Tempe, Arizona, USA.

Green Science Policy Institute , Berkeley, California, USA.

出版信息

Environ Health Perspect. 2017 Jun 20;125(6):064501. doi: 10.1289/EHP1788.

Abstract

documents a consensus of more than 200 scientists and medical professionals on the hazards of and lack of demonstrated benefit from common uses of triclosan and triclocarban. These chemicals may be used in thousands of personal care and consumer products as well as in building materials. Based on extensive peer-reviewed research, this statement concludes that triclosan and triclocarban are environmentally persistent endocrine disruptors that bioaccumulate in and are toxic to aquatic and other organisms. Evidence of other hazards to humans and ecosystems from triclosan and triclocarban is presented along with recommendations intended to prevent future harm from triclosan, triclocarban, and antimicrobial substances with similar properties and effects. Because antimicrobials can have unintended adverse health and environmental impacts, they should only be used when they provide an evidence-based health benefit. Greater transparency is needed in product formulations, and before an antimicrobial is incorporated into a product, the long-term health and ecological impacts should be evaluated. https://doi.org/10.1289/EHP1788.

摘要

记录了200多名科学家和医学专业人员就三氯生和三氯卡班常见用途的危害以及缺乏已证实的益处达成的共识。这些化学物质可用于数千种个人护理和消费品以及建筑材料中。基于广泛的同行评审研究,该声明得出结论,三氯生和三氯卡班是环境持久性内分泌干扰物,会在水生生物和其他生物体内生物累积并对其有毒害作用。文中还介绍了三氯生和三氯卡班对人类和生态系统的其他危害证据,以及旨在防止三氯生、三氯卡班和具有类似性质和作用的抗菌物质未来造成危害的建议。由于抗菌剂可能会产生意想不到的健康和环境负面影响,因此只有在有循证健康益处时才应使用。产品配方需要更高的透明度,在将抗菌剂纳入产品之前,应评估其对长期健康和生态的影响。https://doi.org/10.1289/EHP1788

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