From the *Division of Nuclear Medicine, Department of Radiology, and †Division of Urology, Department of Surgery, McGill University, Montreal, Quebec, Canada.
Clin Nucl Med. 2017 Aug;42(8):624-625. doi: 10.1097/RLU.0000000000001731.
A 74-year-old man with newly diagnosed prostate cancer underwent Ga-PSMA PET/CT, which demonstrated intense uptake in and adjacent the L2 vertebral body. Subsequent MRI of the lumbar spine showed an aggressive L2 hemangioma with adjacent soft tissue extension. There was congruence of the intraosseous and extraosseous components of the hemangioma and the PSMA PET uptake. This is a rare but important potential pitfall in Ga-PSMA PET/CT-a soft tissue lesion with intense tracer uptake related not to a nodal metastasis of prostate cancer but to extraosseous extension of an aggressive vertebral body hemangioma.
一位 74 岁的男性被诊断出患有前列腺癌,随后进行了 Ga-PSMA PET/CT 检查,结果显示 L2 椎体及其邻近部位有强烈摄取。随后进行的腰椎 MRI 显示 L2 椎体侵袭性血管瘤,伴有邻近软组织延伸。血管瘤的骨内和骨外成分与 PSMA PET 摄取相一致。这是 Ga-PSMA PET/CT 中一个罕见但重要的潜在陷阱——软组织病变摄取强烈示踪剂,与前列腺癌的淋巴结转移无关,而是与侵袭性椎体血管瘤的骨外延伸有关。