Mott Sarah E, Hunter William J, Silva Edibaldo, Huerter Christopher J
Division of Dermatology, Creighton University School of Medicine, Omaha, Nebraska, USA.
Department of Pathology, Creighton University School of Medicine, Omaha, Nebraska, USA.
Cutis. 2017 May;99(5):356-362.
Basal cell carcinoma (BCC) is a common nonmelanoma skin cancer with increasing incidence in the United States and worldwide. It is strongly linked to UV radiation exposure and typically is slow growing. Malignancy in BCCs is due to local growth and invasion rather than metastasis, and the prognosis is generally favorable. We report the case of a 60-year-old man with a large, locally destructive giant BCC on the right side of the upper back that was successfully treated via complete surgical excision (SE) and did not recur in the subsequent 36 months. We review the indications, evidence, advantages, and disadvantages associated with multiple surgical and nonsurgical treatment modalities available for the management of giant BCCs.
基底细胞癌（BCC）是一种常见的非黑色素瘤皮肤癌，在美国及全球范围内发病率都在上升。它与紫外线辐射暴露密切相关，通常生长缓慢。BCC的恶性程度源于局部生长和侵袭而非转移，其预后总体良好。我们报告了一例60岁男性患者，其右上背部有一个巨大的、具有局部破坏性的BCC，通过完整手术切除（SE）成功治疗，且在随后的36个月中未复发。我们回顾了与多种可用于治疗巨大BCC的手术和非手术治疗方式相关的适应证、证据、优缺点。
