Thi S S, Parker D M, Swe L L, Pukrittayakamee S, Ling C L, Amornpaisarnloet K, Vincenti-Delmas M, Nosten F H
Shoklo Malaria Research Unit, Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Mae Sot, Tak.
Shoklo Malaria Research Unit, Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Mae Sot, Tak, Mahidol-Oxford Tropical Medicine Research Unit.
Int J Tuberc Lung Dis. 2017 Jul 1;21(7):753-758. doi: 10.5588/ijtld.16.0658.
Multidrug-resistant tuberculosis (MDR-TB) is a growing public health threat in South-East Asia. TB is typically a disease of poverty and can be spread by infectious humans who migrate from one region to another.
We interviewed 20 MDR-TB patients on the Thailand-Myanmar border with regard to their migration histories. Migration origins and destinations were mapped.
All but one participant had a history of migration, and maps of migration ranges revealed wide geographic dispersal. Most described living and work conditions that could contribute to the spread of drug-resistant TB, including numerous contacts and crowded living quarters.
Our results show that at least some migrant workers in the region carry MDR-TB, and indicate that this subgroup of the population is important with regard to the transmission of MDR-TB throughout the region. Migrants in this region come into contact with high numbers of people and may be able to spread the disease across wide geographic ranges. Access to diagnosis and treatment and socio-economic development are at least as important as any TB control measures, meaning that innovative and bold approaches that extend across international borders are needed to address these problems.
耐多药结核病（MDR-TB）对东南亚地区的公共卫生构成了日益严重的威胁。结核病通常是一种贫困相关疾病，可由从一个地区迁移到另一个地区的具有传染性的人传播。
我们就迁移历史采访了泰国-缅甸边境的20名耐多药结核病患者。绘制了迁移来源地和目的地地图。
除一名参与者外，其他所有人都有迁移史，迁移范围地图显示出广泛的地理扩散。大多数人描述了可能导致耐多药结核病传播的生活和工作条件，包括大量接触和拥挤的居住环境。
我们的结果表明，该地区至少有一些流动工人携带耐多药结核病，这表明这一人群亚组在耐多药结核病在整个地区的传播方面具有重要意义。该地区的流动工人与大量人员接触，可能能够在广泛的地理范围内传播疾病。获得诊断和治疗以及社会经济发展至少与任何结核病控制措施一样重要，这意味着需要采取跨越国界的创新和大胆方法来解决这些问题。
