Management of child MDR-TB contacts across countries in the WHO European Region: a survey of current practice.
作者信息
Turkova A, Tebruegge M, Brinkmann F, Tsolia M, Mouchet F, Kampmann B, Seddon J A
机构信息
Medical Research Council Clinical Trials Unit at University College London, London, Department of Paediatric Infectious Diseases, Great Ormond Street Hospital, London.
Academic Unit of Clinical & Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton, Southampton Respiratory Biomedical Research Unit, Southampton University Hospital NHS Foundation Trust, Southampton, Department of Paediatric Infectious Diseases & Immunology, Evelina London Children's Hospital, Guy's and St. Thomas' NHS Foundation Trust, London, UK.
出版信息
Int J Tuberc Lung Dis. 2017 Jul 1;21(7):774-777. doi: 10.5588/ijtld.16.0949.
The World Health Organization European Region has one of the highest rates of multidrug-resistant tuberculosis (MDR-TB) in the world, resulting in many vulnerable children being exposed each year. Evidence for preventive therapy following MDR-TB exposure is limited and current guidance is conflicting. An internet-based survey was performed to determine clinical practice in this region. Seventy-two clinicians from 25 countries participated. Practices related to screening and decision-making were highly variable. Just over half provided preventive therapy for children exposed to MDR-TB; the only characteristic associated with provision was practice within the European Union (adjusted OR 4.07, 95%CI 1.33-12.5).
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