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精准设定癌症预防重点:数据、文献与专家意见的综合分析

Precision in Setting Cancer Prevention Priorities: Synthesis of Data, Literature, and Expert Opinion.

作者信息

Girschik Jennifer, Miller Laura Jean, Addiscott Tony, Daube Mike, Katris Paul, Ransom David, Slevin Terry, Threlfall Tim, Weeramanthri Tarun Stephen

机构信息

Public Health Division, Department of Health Western Australia, Perth, WA, Australia.

Health Consumers Council, Perth, WA, Australia.

出版信息

Front Public Health. 2017 Jun 6;5:125. doi: 10.3389/fpubh.2017.00125. eCollection 2017.

DOI:10.3389/fpubh.2017.00125
PMID:28634579
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5459884/
Abstract

Cancer will continue to be a leading cause of ill health and death unless we can capitalize on the potential for 30-40% of these cancers to be prevented. In this light, cancer prevention represents an enormous opportunity for public health, potentially saving much of the pain, anguish, and cost associated with treating cancer. However, there is a challenge for governments, and the wider community, in prioritizing cancer prevention activities, especially given increasing financial constraints. This paper describes a method for identifying cancer prevention priorities. This method synthesizes detailed cancer statistics, expert opinion, and the published literature for the priority setting process. The process contains four steps: assessing the impact of cancer types; identifying cancers with the greatest impact; considering opportunities for prevention; and combining information on impact and preventability. The strength of our approach is that it is straightforward, transparent and reproducible for other settings. Applying this method in Western Australia produced a priority list of seven adult cancers which were identified as having not only the biggest impact on the community but also the best opportunities for prevention. Work conducted in an additional project phase went on to present data on these priority cancers to a public consultation and develop an agenda for action in cancer prevention.

摘要

除非我们能够利用预防30%-40%癌症的潜力,否则癌症将继续成为健康不良和死亡的主要原因。有鉴于此,癌症预防对公共卫生而言是一个巨大机遇,有可能避免许多与癌症治疗相关的痛苦、 anguish和成本。然而,对于政府及更广泛的社区来说,在确定癌症预防活动的优先次序方面存在挑战,尤其是在财政约束日益增加的情况下。本文描述了一种确定癌症预防优先事项的方法。该方法在优先事项设定过程中综合了详细的癌症统计数据、专家意见和已发表的文献。该过程包括四个步骤:评估癌症类型的影响;确定影响最大的癌症;考虑预防机会;以及综合影响和可预防性方面的信息。我们方法的优势在于它简单明了、透明且可在其他环境中重复使用。在西澳大利亚应用该方法得出了一份七种成人癌症的优先清单,这些癌症不仅被确定对社区影响最大,而且预防机会最佳。在另外一个项目阶段开展的工作继续向公众咨询提供这些优先癌症的数据,并制定癌症预防行动议程。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d151/5459884/7508f1e342b9/fpubh-05-00125-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d151/5459884/7508f1e342b9/fpubh-05-00125-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d151/5459884/7508f1e342b9/fpubh-05-00125-g001.jpg

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Personal habits and indoor combustions.个人习惯与室内燃烧
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Association of Endometrial Cancer Risk With Postmenopausal Bleeding in Women: A Systematic Review and Meta-analysis.女性绝经后出血与子宫内膜癌风险的关联:一项系统评价和荟萃分析。
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Preventability of cancer: the relative contributions of biologic and social and physical environmental determinants of cancer mortality.癌症的可预防性:生物和社会及物理环境决定因素对癌症死亡率的相对贡献。
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Epidemiology - identifying the causes and preventability of cancer?流行病学——确定癌症的病因及可预防性?
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