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一项预防妊娠期糖尿病的随机生活方式干预:对妊娠至产后自评健康的影响。

A randomized lifestyle intervention preventing gestational diabetes: effects on self-rated health from pregnancy to postpartum.

机构信息

a Department of Sports and Exercise Medicine, Clinicum , University of Helsinki , Helsinki , Finland.

b Foundation for Sports and Exercise Medicine , Clinic for Sports and Exercise Medicine , Helsinki , Finland.

出版信息

J Psychosom Obstet Gynaecol. 2018 Mar;39(1):1-6. doi: 10.1080/0167482X.2017.1286642. Epub 2017 Feb 9.

Abstract

INTRODUCTION

The purpose was to examine the effects of a randomized lifestyle intervention on self-rated health from pregnancy to postpartum in participants at high risk for gestational diabetes mellitus.

METHODS

We included 266 women with a history of gestational diabetes and/or prepregnancy BMI ≥30 kg/m. The intervention group (n = 144) received individualized counseling on diet, physical activity, and weight management from trained nurses at six timepoints between the first trimester of pregnancy and 12 months postpartum, and met three times with a dietitian. The control group (n = 122) received standard antenatal care. We assessed self-rated health at the six timepoints by means of a single question with five response options ranging from good (1) to poor (5). Baseline-adjusted mean changes in self-rated health level were assessed with a mixed model for repeated measure methods.

RESULTS

The mean (SD) for self-rated health at baseline was 1.8 (0.8) in the intervention group and 2.1 (0.9) in the control group (p = 0.006). Self-rated health varied over time (time effect p < 0.001) and was the poorest in the third trimester. The sample indicated that self-rated health improved in the intervention group and deteriorated in the control group from the first trimester to 12 months postpartum, but the difference between the groups did not reach statistical significance (group effect p = 0.064).

DISCUSSION

The self-rated health level varied over time from the first trimester of pregnancy to 12 months postpartum in women at risk for gestational diabetes. Improving self-rated health among high-risk pregnant women through lifestyle intervention calls for further research.

摘要

简介

本研究旨在探讨随机生活方式干预对患有妊娠期糖尿病高危因素的孕妇从妊娠到产后自我报告健康状况的影响。

方法

我们纳入了 266 名有妊娠期糖尿病病史和/或孕前 BMI≥30kg/m²的女性。干预组(n=144)在妊娠早期至产后 12 个月期间接受了 6 次由经过培训的护士提供的个性化饮食、身体活动和体重管理咨询,并与营养师会面 3 次。对照组(n=122)接受了标准的产前护理。我们通过一个包含 5 个选项(从好到差)的单一问题,在 6 个时间点评估自我报告的健康状况。采用混合模型重复测量方法评估自我报告健康水平的基线调整后平均变化。

结果

干预组自我报告健康状况的平均(SD)为 1.8(0.8),对照组为 2.1(0.9)(p=0.006)。自我报告的健康状况随时间而变化(时间效应 p<0.001),且在孕晚期最差。该样本表明,自我报告的健康状况在干预组中从妊娠早期到产后 12 个月有所改善,而在对照组中则恶化,但组间差异无统计学意义(组间效应 p=0.064)。

讨论

在患有妊娠期糖尿病高危因素的女性中,从妊娠早期到产后 12 个月,自我报告的健康状况随时间而变化。通过生活方式干预改善高危孕妇的自我报告健康状况需要进一步研究。

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