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两种同手性[Ru(bpy)dppz]配合物与聚（U）·聚（A）*聚（U）三链体RNA的结合差异

Binding Differences of Two Homochiral [Ru(bpy)dppz] Complexes with poly(U)·poly(A)*poly(U) Triplex RNA.

作者信息

Peng Meng-Na, Zhu Zhi-Yuan, Tan Li-Feng

机构信息

Key Laboratory of Environment-friendly Chemistry and Application in Ministry of Education and ‡College of Chemistry, Xiangtan University , Xiangtan 411105, China.

出版信息

Inorg Chem. 2017 Jul 3;56(13):7312-7315. doi: 10.1021/acs.inorgchem.7b00670. Epub 2017 Jun 21.

DOI:10.1021/acs.inorgchem.7b00670
PMID:28636339
Abstract

The first investigation of chiral ruthenium(II) complexes Δ- and Λ-[Ru(bpy)dppz] and triplex RNA poly(U)·poly(A)*poly(U) was carried out, which showed that Δ enantiomer displayed significant ability in stabilizing model triplex RNA.

摘要

对手性钌（II）配合物Δ-和Λ-[Ru(bpy)dppz]与三链RNA聚（U）·聚（A）*聚（U）进行了首次研究，结果表明Δ对映体在稳定模型三链RNA方面具有显著能力。

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Binding Differences of Two Homochiral [Ru(bpy)dppz] Complexes with poly(U)·poly(A)*poly(U) Triplex RNA.两种同手性[Ru(bpy)dppz]配合物与聚（U）·聚（A）*聚（U）三链体RNA的结合差异
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引用本文的文献

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Biophysical insights into the interaction of two enantiomers of Ru(II) complex [Ru(bpy)(7-CH-dppz)] with the RNA poly(U-A⁎U) triplex.从生物物理角度研究两种对映体的 Ru(II) 配合物 [Ru(bpy)(7-CH-dppz)] 与 RNA 聚(U-A⁎U)三螺旋的相互作用。
J Biol Inorg Chem. 2020 Dec;25(8):1085-1095. doi: 10.1007/s00775-020-01825-9. Epub 2020 Oct 11.
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Flexibility and thermal dynamic stability increase of dsDNA induced by Ru(bpy)dppz based on AFM and HRM technique.
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