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饮茶与中国老年人群认知功能障碍有关。

Tea consumption is associated with cognitive impairment in older Chinese adults.

机构信息

a Jiangsu Key Laboratory of Preventive and Translational Medicine for Geriatric Diseases, School of Public Health , Medical College of Soochow University , 199 Ren Ai Road, Suzhou , China.

b School of Basic Medicine , Medical College of Soochow University , 199 Ren Ai Road, Suzhou , China.

出版信息

Aging Ment Health. 2018 Sep;22(9):1232-1238. doi: 10.1080/13607863.2017.1339779. Epub 2017 Jun 21.

Abstract

OBJECTIVE

To explore the association between tea consumption and cognitive impairment (CoI).

METHODS

4579 adults (≥60 years) from the Weitang Geratric Diseases Study were assessed for characteristics of tea consumption and cognitive function by administering questionnaires and the Abbreviated Mental Test (AMT), respectively. We divided the subjects into normal cognitive function group (AMT score ≥8) and CoI group (AMT score ≤7).   The association between tea consumption and risk of CoI was determined by logistic regression models.

RESULTS

The least-squared means of the AMT scores for the subjects who seldom consumed tea were less favorable than those who habitually consumed tea. An inverse association was found between tea consumption (of any type) and prevalence of CoI (odds ratio = 0.74, 95% confidence interval = 0.57-0.98, P = 0.032). Interestingly, the protective correlation of tea was more obvious in never smokers (odds ratio = 0.63), but vanished in current/former smokers (odds ratio = 1.10). In never smokers, frequency of tea consumption was significantly associated with CoI (P for trend = 0.010).

CONCLUSION

Habitual tea consumption is suggested to be associated with a decreased risk of CoI among elders in Suzhou, and a higher frequency of tea consumption was associated with a lower prevalence of CoI among never smokers.

摘要

目的

探讨饮茶与认知障碍(CoI)的关系。

方法

对来自卫塘老年病研究的 4579 名成年人(≥60 岁)进行问卷调查和简易精神状态检查(AMT),以评估其饮茶习惯和认知功能。我们将受试者分为正常认知功能组(AMT 评分≥8)和 CoI 组(AMT 评分≤7)。通过逻辑回归模型确定饮茶与 CoI 风险的关联。

结果

少饮茶者的 AMT 评分的最小二乘均值不如经常饮茶者。饮茶(任何类型)与 CoI 的患病率呈负相关(比值比=0.74,95%置信区间=0.57-0.98,P=0.032)。有趣的是,在从不吸烟者中,茶的保护相关性更为明显(比值比=0.63),但在当前/曾经吸烟者中则消失(比值比=1.10)。在从不吸烟者中,饮茶频率与 CoI 显著相关(趋势 P 值=0.010)。

结论

习惯性饮茶与苏州老年人 CoI 风险降低有关,从不吸烟者中饮茶频率越高,CoI 患病率越低。

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