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经皮胆囊造瘘术是高危患者急性胆囊炎的一种良好替代治疗方法吗?

Is Percutaneous Cholecystostomy a Good Alternative Treatment for Acute Cholecystitis in High-Risk Patients?

作者信息

Papis Davide, Khalifa Eiman, Bhogal Ricky, Nair Amit, Khan Saboor, Hamady Zaed, Ahmed Jawad, Marangoni Gabriele

出版信息

Am Surg. 2017 Jun 1;83(6):623-627.

Abstract

Cholecystectomy is the treatment of choice for acute cholecystitis but the management of high-risk surgical patients is a difficult dilemma. Percutaneous cholecystostomy (PC) could represent a safer and less invasive option. The aim of the study was to assess the outcomes of PC in high-risk patients. This is a retrospective single-center study; data were collected from our hospital electronic record system. From February 2009 to March 2014, there were 753 patients admitted with acute cholecystitis. Of these 39 were considered high risk for surgery and underwent PC during their hospital stay. The radiological approach was transperitoneal in 29 patients and transhepatic in 10 patients. Median follow-up was 19 months. There were 27 males (69.2%) and 12 females (30.8%) with a mean age of 72 years (range 41-90 years). Twenty-seven patients had PC as definitive treatment (group A) and 12 patients as a bridge to cholecystectomy (group B). There were no postprocedure complications. Five patients in group A were readmitted once with another episode of cholecystitis after PC (18.5%), one patient in group B was readmitted with cholecystitis after two years before proceeding to cholecystectomy, and two patients were readmitted after cholecystectomy (16.6%) for intra-abdominal collections treated with percutaneous radiological drainage. Seven patients died (17.9%) as a result of severe biliary sepsis during their index hospital admission. PC is a safe approach in high-risk patients with acute cholecystitis and can provide satisfactory long-term results when cholecystectomy is not a viable option.

摘要

胆囊切除术是急性胆囊炎的首选治疗方法,但高危手术患者的管理是一个棘手的难题。经皮胆囊造瘘术(PC)可能是一种更安全、侵入性更小的选择。本研究的目的是评估PC在高危患者中的治疗效果。这是一项回顾性单中心研究;数据从我院电子病历系统收集。2009年2月至2014年3月,共有753例急性胆囊炎患者入院。其中39例被认为手术风险高,并在住院期间接受了PC治疗。29例患者采用经腹途径,10例患者采用经肝途径。中位随访时间为19个月。男性27例(69.2%),女性12例(30.8%),平均年龄72岁(范围41 - 90岁)。27例患者将PC作为确定性治疗(A组),12例患者将PC作为胆囊切除术的桥梁(B组)。术后无并发症发生。A组5例患者在PC术后因再次发作胆囊炎而再次入院(18.5%),B组1例患者在进行胆囊切除术前行两年因胆囊炎再次入院,2例患者在胆囊切除术后因腹腔内积液经皮放射引流治疗而再次入院(16.6%)。7例患者在首次住院期间因严重胆源性败血症死亡(17.9%)。对于急性胆囊炎高危患者,PC是一种安全的治疗方法,当胆囊切除术不可行时,可提供满意的长期治疗效果。

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