Kesim Çağrı, Özen Özgür
Başkent University, Konya Hospital, Department of Radiology, Interventional Radiology Section, Turkey.
Başkent University, Ankara Hospital, Department of Radiology, Interventional Radiology Section, Turkey.
Heliyon. 2023 Apr 18;9(5):e15601. doi: 10.1016/j.heliyon.2023.e15601. eCollection 2023 May.
We aimed to investigate the extent to which ultrasound (US)-guided percutaneous cholecystostomy (PC) is used as a bridging or definitive therapy for grade II and III acute cholecystitis and whether this treatment causes significant changes in C-reactive protein (CRP) and direct bilirubin (DB) levels in the first 72 h and the first three weeks.
We included 145 consecutive patients who underwent PC over 17 years. No patient had cirrhosis. PC was performed in the interventional radiology department under US guidance.
US-guided PC was the definitive treatment for more than half of the patients (51.7%) and decreased DB levels significantly more than CRP levels.
No statistically significant correlation between those whose CRP and DB levels normalized within three weeks and those who did not and required a second invasive procedure. Nevertheless, the bridging treatment group was significantly older than the definitive treatment group.
我们旨在研究超声（US）引导下经皮胆囊造瘘术（PC）作为II级和III级急性胆囊炎的桥接治疗或确定性治疗的应用程度，以及这种治疗是否会在最初72小时和前三周内导致C反应蛋白（CRP）和直接胆红素（DB）水平发生显著变化。
我们纳入了17年间连续接受PC治疗的145例患者。所有患者均无肝硬化。PC在介入放射科超声引导下进行。
超声引导下PC是超过半数患者（51.7%）的确定性治疗方法，且DB水平的下降幅度明显大于CRP水平。
在三周内CRP和DB水平恢复正常的患者与未恢复正常且需要进行二次侵入性手术的患者之间，无统计学显著相关性。然而，桥接治疗组的年龄明显大于确定性治疗组。
