Steel N R, Bingle J P, Ramsay I D, Kendall-Taylor P
Postgrad Med J. 1985 Aug;61(718):717-20. doi: 10.1136/pgmj.61.718.717.
The development of spontaneous hyperthyroidism following primary hypothyroidism is an unusual occurrence. We report two cases of confirmed primary hypothyroidism who subsequently became hyperthyroid. Thyroid stimulating antibodies were present in the sera of both patients during the hyperthyroid state. The significance of this sequence of events is discussed and a possible explanation proposed.
原发性甲状腺功能减退症后发生自发性甲状腺功能亢进症是一种不寻常的情况。我们报告了两例确诊的原发性甲状腺功能减退症患者,他们随后发展为甲状腺功能亢进。在甲状腺功能亢进状态下,两名患者的血清中均存在甲状腺刺激抗体。本文讨论了这一系列事件的意义并提出了一种可能的解释。