Ammar Hussam, Govindu Rukma, Fouda Ragai, Zohdy Wael, Supsupin Emilio
Department of Internal Medicine, The University of Texas Health Science Center at Houston, Houston, Texas, USA.
Department of Internal medicine, Kasr Al Aini Hospital, Cairo University, Cairo, Egypt.
J Community Hosp Intern Med Perspect. 2017 Jun 6;7(2):73-78. doi: 10.1080/20009666.2017.1332317. eCollection 2017 Mar.
: Neuroimaging is contributing to the rising costs of dizziness evaluation. This study examined the rate of central neurological causes of dizziness, relevant clinical predictors, and the costs and diagnostic yields of neuroimaging in dizziness assessment. : We retrospectively reviewed the records of 521 adult patients who visited the hospital during a 12-month period with dizziness as the chief complaint. Clinical findings were analyzed using Fisher's exact test to determine how they correlated with central neurological causes of dizziness identified by neuroimaging. Costs and diagnostic yields of neuroimaging were calculated. : Of the 521 patients, 1.5% had dizziness produced by central neurological causes. Gait abnormalities, limb ataxia, diabetes mellitus, and the existence of multiple neurological findings predicted central causes. Cases were associated with gait abnormalities, limb ataxia, diabetes mellitus, and the existence of multiple neurological findings . Brain computed tomography (CT) and magnetic resonance imaging (MRI) were performed in 42% and 9.5% of the examined cases, respectively, with diagnostic yields of 3.6% and 12%, respectively. Nine cases of dizziness were diagnosed from 269 brain scans, costing $607 914. : Clinical evaluation can predict the presence of central neurological causes of dizziness, whereas neuroimaging is a costly and low-yield approach. Guidelines are needed for physicians, regarding the appropriateness of ordering neuroimaging studies. : OR: odds ratio; CI: confidence interval; ED: emergency department; CT: computed tomography; MRI: magnetic resonance imaging; HINTS: Head impulse, Nystagmus, Test of skew.
神经影像学检查致使头晕评估成本不断上升。本研究调查了头晕的中枢神经病因发生率、相关临床预测因素以及神经影像学检查在头晕评估中的成本和诊断率。
我们回顾性分析了521例以头晕为主诉在12个月内就诊于我院的成年患者的病历。采用Fisher精确检验分析临床检查结果,以确定其与神经影像学检查所发现的头晕中枢神经病因之间的相关性。计算神经影像学检查的成本和诊断率。
在521例患者中,1.5%由中枢神经病因导致头晕。步态异常、肢体共济失调、糖尿病以及存在多种神经学表现可预测中枢病因。病例与步态异常、肢体共济失调、糖尿病以及存在多种神经学表现有关。分别有42%和9.5%的受检病例进行了脑部计算机断层扫描(CT)和磁共振成像(MRI)检查,诊断率分别为3.6%和12%。从269次脑部扫描中诊断出9例头晕病例,花费607914美元。
临床评估可预测头晕的中枢神经病因,而神经影像学检查成本高昂且诊断率低。需要为医生制定关于开具神经影像学检查的适当性的指南。
比值比;CI:置信区间;ED:急诊科;CT:计算机断层扫描;MRI:磁共振成像;HINTS:头脉冲、眼球震颤、斜视试验