Berraondo Pedro, Labiano Sara, Minute Luna, Etxeberria Iñaki, Vasquez Marcos, Sanchez-Arraez Alvaro, Teijeira Alvaro, Melero Ignacio
Program of Immunology and Immunotherapy, Center for Applied Medical Research (CIMA), Pamplona, Spain.
Navarra Institute for Health Research (IDISNA), Pamplona, Spain.
Oncoimmunology. 2017 May 2;6(5):e1306619. doi: 10.1080/2162402X.2017.1306619. eCollection 2017.
Lessons learned over decades on the use of gene and cell therapies have found clinical applicability in the field of cancer immunotherapy. On December 16, 2016 a symposium was held in Pamplona (Spain) to analyze and discuss the critical points for the clinical success of adoptive cell transfer strategies in cancer immunotherapy. Cellular immunotherapy is being currently exploited for the development of new cancer vaccines using manipulated dendritic cells or to enhance the number of effector cells, transferring reinvigorated NK cells or T cells. In this meeting report, we summarize the main topics covered and provide an overview of the field of cellular immunotherapy.
数十年来在基因和细胞疗法应用方面所汲取的经验教训已在癌症免疫治疗领域得到临床应用。2016年12月16日，一场研讨会在西班牙潘普洛纳召开，旨在分析和讨论癌症免疫治疗中过继性细胞转移策略取得临床成功的关键点。目前，细胞免疫疗法正被用于开发新型癌症疫苗，方法是利用经操控的树突状细胞，或者增加效应细胞的数量，即转移经恢复活力的自然杀伤细胞或T细胞。在本会议报告中，我们总结了所涵盖的主要议题，并对细胞免疫治疗领域进行了概述。
