Sharma Navneet, Lee Justin, Youssef Irini, Salifu Moro O, McFarlane Samy I
Department of Medicine, Divisions of Endocrinology and Nephrology, New York, USA.
J Sleep Disord Ther. 2017 Mar;6(1). doi: 10.4172/2167-0277.1000260. Epub 2017 Mar 10.
Cardiovascular disease (CVD) is the main cause of death among adult men and women in the USA and impacts millions around the globe. Traditional risk factors for CVD include obesity, diabetes, hypertension and dyslipidemia. The modern-day epidemic of obesity not only increased the rate of CVD but also ushered in an additional CVD risk factor to be added to the list; that is obstructive sleep apnea (OSA). In this review, we discuss the growing epidemic of obesity and OSA, highlighting the common pathogenic hypotheses linking these risk factors to CVD. We will also highlight the therapeutic rationale of OSA as a way to reduce CVD risk.
心血管疾病（CVD）是美国成年男性和女性的主要死因，并且影响着全球数百万人。CVD的传统风险因素包括肥胖、糖尿病、高血压和血脂异常。现代肥胖流行不仅增加了CVD的发病率，还引入了另一个要列入清单的CVD风险因素，即阻塞性睡眠呼吸暂停（OSA）。在这篇综述中，我们讨论肥胖和OSA日益流行的情况，强调将这些风险因素与CVD联系起来的常见致病假说。我们还将强调OSA作为降低CVD风险方法的治疗原理。
