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大麻与心肌梗死:风险因素及发病机制见解

Cannabis and Myocardial Infarction: Risk Factors and Pathogenetic Insights.

作者信息

Lee Justin, Sharma Navneet, Kazi Farnam, Youssef Irini, Myers Alyson, Marmur Jonathan D, Salifu Moro O, McFarlane Samy I

机构信息

State University of New York-Downstate, Department of Medicine, Divisions of Cardiovascular Medicine and Endocrinology, Brooklyn, NY 11203, USA.

出版信息

Scifed J Cardiol. 2017;1(1). Epub 2017 Jul 22.

PMID:30294730
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6173198/
Abstract

Cannabis use in the US is rising with increased legalization. It has been noted that there is a five-fold increase risk of Myocardial Infarctions (MI) in the first hour after cannabis use. Traditional risk factors for MI include diabetes, hypertension and dyslipidemia. The rising use of cannabis may have ushered in an additional MI risk factor to be added to the list; that is cannabis. In this review, we discuss the growing use of cannabis and potential link with MI, highlighting the common pathogenic hypotheses linking these risk factors.

摘要

在美国,随着大麻合法化程度的提高,大麻的使用量正在上升。据指出,在使用大麻后的第一小时内,心肌梗死(MI)的风险增加了五倍。心肌梗死的传统风险因素包括糖尿病、高血压和血脂异常。大麻使用量的上升可能引入了另一个需要列入清单的心肌梗死风险因素,即大麻。在这篇综述中,我们讨论了大麻使用的增加及其与心肌梗死的潜在联系,强调了将这些风险因素联系起来的常见致病假说。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/94fa/6173198/83db8bfbc384/nihms964257f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/94fa/6173198/83db8bfbc384/nihms964257f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/94fa/6173198/83db8bfbc384/nihms964257f1.jpg

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PLoS One. 2017 Apr 12;12(4):e0175133. doi: 10.1371/journal.pone.0175133. eCollection 2017.
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