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欧洲疥疮管理指南。

European guideline for the management of scabies.

机构信息

Department of Dermato-Pediatry, Colentina Clinical Hospital, "Carol Davila" University of Medicine and Pharmacy, Bucharest, Romania.

Department of Dermatology, Hôpital Henri Mondor AP-HP, Créteil, France.

出版信息

J Eur Acad Dermatol Venereol. 2017 Aug;31(8):1248-1253. doi: 10.1111/jdv.14351. Epub 2017 Jun 22.

Abstract

Scabies is caused by Sarcoptes scabiei var. hominis. The disease can be sexually transmitted. Patients' main complaint is nocturnal itch. Disseminated, excoriated, erythematous papules are usually seen on the anterior trunk and limbs. Crusted scabies occurs in immunocompromised hosts and may be associated with reduced or absent pruritus. Recommended treatments are permethrin 5% cream, oral ivermectin and benzyl benzoate 25% lotion. Alternative treatments are malathion 0.5% aqueous lotion, ivermectin 1% lotion and sulphur 6-33% cream, ointment or lotion. Crusted scabies therapy requires a topical scabicide and oral ivermectin. Mass treatment of large populations with endemic disease can be performed with a single dose of ivermectin (200 micrograms/kg of bodyweight). Partner management needs a look-back period of 2 months. Screening for other STI is recommended. Patients and close contacts should avoid sexual contact until completion of treatment and should strictly observe personal hygiene rules when living in crowded spaces. Written information should be provided to suspected cases.

摘要

疥疮是由人疥螨引起的。这种疾病可以通过性接触传播。患者的主要症状是夜间瘙痒。常见的症状是在前胸、躯干和四肢出现散播性、搔抓性、红斑性丘疹。在免疫功能低下的宿主中,可能会出现结痂性疥疮,其瘙痒可能会减轻或消失。推荐的治疗方法是 5%的扑灭司林乳膏、口服伊维菌素和 25%苯甲酸苄酯洗剂。替代疗法是 0.5%马拉硫磷水剂、1%伊维菌素洗剂和 6%-33%硫磺乳膏、软膏或洗剂。结痂性疥疮的治疗需要局部用杀疥药和口服伊维菌素。对流行地区的大量人群进行集体治疗,可以使用一剂伊维菌素(200 微克/公斤体重)。性伴侣管理需要回溯观察 2 个月。建议筛查其他性传播感染。患者及其密切接触者在完成治疗前应避免性接触,并在居住在拥挤场所时严格遵守个人卫生规则。应向疑似病例提供书面信息。

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