Zhang Ning, He Liangliang, Ni Jia-Xiang
Department of Pain Management, Xuanwu Hospital, Capital medical University Department of Anesthesiology, Beijing Obstetrics and Gynecology Hospital, Capital Medical University, Beijing, China.
Medicine (Baltimore). 2017 Jun;96(25):e7184. doi: 10.1097/MD.0000000000007184.
When the sensory block level (SBL) is ≥T5 or T4, a high incidence of hypotension occurs in parturients after spinal anesthesia. A rapidly ascending SBL is another risk factor for spinal anesthesia-induced hypotension. However, the relationship between the ascension rate of the SBL and spinal anesthesia-induced hypotension remains unclear.After placement in the left lateral position, combined epidural-spinal anesthesia was performed on 140 parturients undergoing caesarean section using the following procedure: no volume preloading, injection site of L3-4 or L4-5, injection rate of 0.1 mL/sec, and administration of 10 mg of 0.5% hyperbaric bupivacaine. A receiver-operating characteristic curve was built to estimate the accuracy of the SBL ascension rate in detecting spinal anesthesia-induced hypotension.The mean time interval from spinal injection to placement in the supine position was 136 ± 10 seconds in all anesthesia procedures. The earliest and most complete records of the SBL started from the 3rd minute after spinal injection. The threshold spread rate corresponding to the highest accuracy for occurrence of hypotension was an SBL of ≥T8 at the 3rd minute after spinal injection, with 82% and 88% sensitivity and specificity, respectively.The ascension rate of an SBL of ≥T8 at the 3rd minute after spinal injection is as a predictor of hypotension in parturients.
当感觉阻滞平面(SBL)≥T5或T4时,剖宫产产妇在脊麻后发生低血压的发生率较高。SBL快速上升是脊麻诱导低血压的另一个危险因素。然而,SBL上升速率与脊麻诱导低血压之间的关系仍不清楚。
将140例行剖宫产的产妇置于左侧卧位后,采用以下方法实施腰麻-硬膜外联合麻醉:不进行容量预负荷,穿刺部位为L3-4或L4-5,注射速率为0.1mL/秒,给予10mg 0.5%的重比重布比卡因。构建受试者工作特征曲线以评估SBL上升速率在检测脊麻诱导低血压中的准确性。
在所有麻醉操作中,从脊麻注射到仰卧位的平均时间间隔为136±10秒。SBL最早且最完整的记录从脊麻注射后第3分钟开始。脊麻注射后第3分钟SBL≥T8时,对应低血压发生最高准确性的阈值扩散速率,敏感性和特异性分别为82%和88%。
脊麻注射后第3分钟SBL≥T8的上升速率可作为预测产妇低血压的指标。