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膝胸卧位孕妇脊髓麻醉的起效时间:一项随机对照研究

Onset Time of Spinal Anaesthesia in Pregnant Females in Knee-Chest Position: A Randomized Controlled Study.

作者信息

Narasimhan Purnima, Garg Heena, Maitra Souvik, Goswami Devalina, Kumar Shailendra, Nisa Neisevilie, Kundu Riddhi, Khanna Puneet

机构信息

Department of Anaesthesiology, Pain Medicine and Critical Care, All India Institute of Medical Sciences, New Delhi, India.

出版信息

Turk J Anaesthesiol Reanim. 2022 Feb;50(1):24-30. doi: 10.5152/TJAR.2021.919.

Abstract

OBJECTIVE

To assess the efficacy of knee-chest position in shortening the time of spinal induction in pregnant women undergoing elective cesarean section. We also assessed for any untoward adverse events that might limit their usefulness in real-life clinical scenarios.

METHODS

Prospective, randomized controlled study was done in maternity operating room of tertiary care institution in 45 ASA II pregnant women undergoing elective cesarean section under spinal anaesthesia. Patients were randomly assigned to groups S (supine) and K (kneechest position). After performing subarachnoid block (9 mg of 0.5% hyperbaric bupivacaine and 25 µg fentanyl) in the sitting position, women in group K were maintained in the knee-chest position for 60 seconds. Time to attain block height of T6 and maximum sensory blockade, intraoperative hemodynamics, Bromage score, intraoperative fluid, vasopressor requirement, and respiratory parameters were recorded. The newborn was evaluated using Apgar scores at 1 and 5 minutes.

RESULTS

Data of 45 patients were analyzed. Time to attain T6 block height (group K=2.1 ± 0.65 minutes, 95% CI: 1.83-2.39; group S=6.4 ± 0.77 minutes, 95% CI: 6.10-6.78) and time to achieve maximum sensory block height were significantly lower in group K (group K=3.2 ± 1.35 minutes, 95% CI: 2.61-3.78; group S=6.6 ± 0.89 min, CI: 6.19-6.98). The degree of motor block was higher in group K than that of group S at 2 minutes (P=.0002), 4 minutes (P < .0001), and 6 minutes (P < .0001), with no difference at 8 minutes. No statistically significant difference was observed in fluids and vasopressors requirement intraoperatively.

CONCLUSIONS

This study provides evidence that the onset of adequate surgical anaesthesia for the cesarean section can be hastened by placing the patient in the knee-chest position for a minute after performing the subarachnoid block in the sitting position.

摘要

目的

评估膝胸位在缩短择期剖宫产孕妇脊髓麻醉诱导时间方面的疗效。我们还评估了可能限制其在实际临床场景中应用的任何不良事件。

方法

在一家三级医疗机构的产科手术室对45例ASA II级择期剖宫产孕妇进行前瞻性随机对照研究,这些孕妇接受脊髓麻醉。患者被随机分为S组(仰卧位)和K组(膝胸位)。在坐位进行蛛网膜下腔阻滞(9 mg 0.5% 重比重布比卡因和25 μg芬太尼)后,K组女性保持膝胸位60秒。记录达到T6阻滞平面的时间、最大感觉阻滞平面、术中血流动力学、布罗玛杰评分、术中液体量、血管升压药需求量和呼吸参数。新生儿在1分钟和5分钟时使用阿普加评分进行评估。

结果

分析了45例患者的数据。K组达到T6阻滞平面的时间(K组 = 2.1 ± 0.65分钟,95% CI:1.83 - 2.39;S组 = 6.4 ± 0.77分钟,95% CI:6.10 - 6.78)和达到最大感觉阻滞平面的时间显著低于S组(K组 = 3.2 ± 1.35分钟,95% CI:2.61 - 3.78;S组 = 6.6 ± 0.89分钟,CI:6.19 - 6.98)。K组在2分钟(P = 0.0002)、4分钟(P < 0.0001)和6分钟(P < 0.0001)时的运动阻滞程度高于S组,8分钟时无差异。术中液体量和血管升压药需求量未观察到统计学显著差异。

结论

本研究提供了证据,表明在坐位进行蛛网膜下腔阻滞后将患者置于膝胸位一分钟可加速剖宫产手术充分麻醉的起效。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8d8d/9154002/d44985b944dd/tjar-50-1-24_f001.jpg

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