Jiao Yuxin, Ren Yanping, Zheng Xiangpeng
Department of Radiology Oncology;Department of Radiology, Fudan University Huadong Hospital, Shanghai 200040, China.
Department of Radiology Oncology, Fudan University Huadong Hospital, Shanghai 200040, China.
Zhongguo Fei Ai Za Zhi. 2017 Jun 20;20(6):407-414. doi: 10.3779/j.issn.1009-3419.2017.06.07.
Precision medicine demands accurate assessment of tumor response to therapies with the purpose of timely optimization or adjustment of the given treatment regimens. Chemoradiation remains the standard of care in advanced lung cancers and imaging-based noninvasive response evaluation could improve therapeutic efficacy and reduce treatment-related severe side effects. In this review, we overviewed the applications and pitfalls of major imaging modalities in response evaluation in lung cancer from a quantitative perspective. The development of radiomics will provide more precise information for treatment predicting, evaluation and prognosis.
精准医学要求准确评估肿瘤对治疗的反应,以便及时优化或调整给定的治疗方案。放化疗仍然是晚期肺癌的标准治疗方法,基于影像学的非侵入性反应评估可以提高治疗效果并减少与治疗相关的严重副作用。在本综述中,我们从定量角度概述了主要成像模态在肺癌反应评估中的应用和陷阱。放射组学的发展将为治疗预测、评估和预后提供更精确的信息。