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本文引用的文献

1
Psychotropic prescribing in seriously violent men with schizophrenia or personality disorder in a UK high security hospital.英国一家高度戒备医院中,针对患有精神分裂症或人格障碍的严重暴力倾向男性的精神药物处方情况。
CNS Spectr. 2016 Feb;21(1):60-9. doi: 10.1017/S1092852915000784. Epub 2016 Jan 4.
2
Cognitive dysfunction in bipolar disorder and schizophrenia: a systematic review of meta-analyses.双相情感障碍和精神分裂症中的认知功能障碍:荟萃分析的系统评价
Neuropsychiatr Dis Treat. 2015 Dec 17;11:3111-25. doi: 10.2147/NDT.S76700. eCollection 2015.
3
The risk of suicide after clozapine discontinuation: Cause for concern.停用氯氮平后自杀的风险:令人担忧的原因。
Ann Clin Psychiatry. 2015 Nov;27(4):253-6.
4
Employment and the associated impact on quality of life in people diagnosed with schizophrenia.就业以及对被诊断为精神分裂症患者生活质量的相关影响。
Neuropsychiatr Dis Treat. 2015 Aug 18;11:2125-42. doi: 10.2147/NDT.S83546. eCollection 2015.
5
Clozapine prescribing in the UK: views and experience of consultant psychiatrists.英国的氯氮平处方:精神科顾问医生的观点与经验
Ther Adv Psychopharmacol. 2015 Apr;5(2):88-96. doi: 10.1177/2045125314566808.
6
Blood Draw Barriers for Treatment with Clozapine and Development of a Point-of-Care Monitoring Device.氯氮平治疗的采血障碍及即时检测监测设备的研发
Clin Schizophr Relat Psychoses. 2018 Spring;12(1):23-30. doi: 10.3371/CSRP.KEBE.070415. Epub 2015 Jul 28.
7
An evaluation of subjective experiences, effects and overall satisfaction with clozapine treatment in a UK forensic service.一项关于英国法医服务中氯氮平治疗的主观体验、效果和总体满意度的评估。
Ther Adv Psychopharmacol. 2015 Jun;5(3):146-50. doi: 10.1177/2045125315581996.
8
Metacognitive Deficits in Schizophrenia: Presence and Associations With Psychosocial Outcomes.精神分裂症中的元认知缺陷:存在情况及其与社会心理结果的关联
J Nerv Ment Dis. 2015 Jul;203(7):530-6. doi: 10.1097/NMD.0000000000000323.
9
Pharmacological management of persistent hostility and aggression in persons with schizophrenia spectrum disorders: a systematic review.精神分裂症谱系障碍患者持续性敌意和攻击行为的药物治疗:一项系统评价
J Neuropsychiatry Clin Neurosci. 2014 Fall;26(4):283-312. doi: 10.1176/appi.neuropsych.13110335.
10
Influence of Criminal Justice Involvement and Psychiatric Diagnoses on Treatment Costs Among Adults With Serious Mental Illness.刑事司法介入和精神疾病诊断对重度精神疾病成年人治疗费用的影响。
Psychiatr Serv. 2015 Sep;66(9):907-9. doi: 10.1176/appi.ps.201500134. Epub 2015 May 15.

氯氮平在减少法医人群中的攻击和暴力行为中的作用。

Clozapine in Reducing Aggression and Violence in Forensic Populations.

机构信息

Department of Psychiatry, University of Maryland School of Medicine, 630 W Fayette St, Baltimore, MD, 21201, USA.

Spring Grove Hospital and Maryland Psychiatric Research Center, University of Maryland School of Medicine, PO Box 21247, Baltimore, MD, 21228, USA.

出版信息

Psychiatr Q. 2018 Mar;89(1):157-168. doi: 10.1007/s11126-017-9521-z.

DOI:10.1007/s11126-017-9521-z
PMID:28643049
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5930356/
Abstract

Popular media often portray people with a mental illness as being aggressive, violent, and incarcerated as a result of their behavior. Despite exaggeration in the media, risks for some aggressive behaviors are in fact higher in individuals with schizophrenia. This is often the case with influence of comorbid substance use disorders. It is essential that mental health professionals are aware of treatments that may help with attenuating and treating behaviors that contribute to violence, aggression and incarceration. This paper reviews violence and incarceration in individuals with schizophrenia as well as recommendations, guidelines and benefits for the use of clozapine in this population. Clozapine remains one of the most underutilized evidence-based medications available in the psychiatric arena in the United States. It is a viable and recommended option in the forensic population and it may be helpful on the path to recovery as well as bring substantial savings to the criminal justice system.

摘要

大众媒体经常将患有精神疾病的人描绘成具有攻击性、暴力和因行为而被监禁的形象。尽管媒体有夸大的成分,但事实上,精神分裂症患者确实存在更高的某些攻击性行为风险。这种情况通常与合并物质使用障碍的影响有关。心理健康专业人员必须了解可能有助于减轻和治疗导致暴力、攻击和监禁的行为的治疗方法。本文回顾了精神分裂症患者的暴力和监禁问题,以及在该人群中使用氯氮平的建议、指南和益处。氯氮平仍然是美国精神病学领域中最未被充分利用的循证药物之一。它是法医学人群中的一种可行且推荐的选择,它可能有助于康复,也可能为刑事司法系统带来大量节省。