Faculty of Pharmacy, The University of Sydney, Sydney, NSW 2006, Australia.
Chem Soc Rev. 2017 Aug 14;46(16):4818-4832. doi: 10.1039/c6cs00693k.
In order to retard the rate of development of antibacterial resistance, the causative agent must be identified as rapidly as possible, so that directed patient treatment and/or contact precautions can be initiated. This review highlights the challenges associated with the detection and identification of pathogenic bacteria, by providing an introduction to the techniques currently used, as well as newer techniques that are in development. Focusing on the chemical basis for these techniques, the review also provides a comparison of their advantages and disadvantages.
为了减缓抗菌耐药性的发展速度，必须尽快确定病原体，以便能够对患者进行有针对性的治疗和/或采取接触预防措施。本综述通过介绍当前使用的技术以及正在开发的新技术，强调了检测和鉴定致病菌所面临的挑战。重点介绍了这些技术的化学基础，还比较了它们的优缺点。
