在嵌合抗原受体T细胞扩增过程中，低白细胞介素-2浓度有利于早期记忆性T细胞而非效应细胞表型的产生。 - Suppr

Low interleukin-2 concentration favors generation of early memory T cells over effector phenotypes during chimeric antigen receptor T-cell expansion.

作者信息

Kaartinen Tanja, Luostarinen Annu, Maliniemi Pilvi, Keto Joni, Arvas Mikko, Belt Heini, Koponen Jonna, Mäkinen Petri I, Loskog Angelica, Mustjoki Satu, Porkka Kimmo, Ylä-Herttuala Seppo, Korhonen Matti

机构信息

Advanced Cell Therapy Centre, Finnish Red Cross Blood Service, Helsinki, Finland.

Advanced Cell Therapy Centre, Finnish Red Cross Blood Service, Helsinki, Finland; Research & Development, Finnish Red Cross Blood Service, Helsinki, Finland.

出版信息

Cytotherapy. 2017 Sep;19(9):1130. doi: 10.1016/j.jcyt.2017.06.003. Epub 2017 Jun 20.

DOI:10.1016/j.jcyt.2017.06.003

PMID:28645733

Abstract

摘要

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Low interleukin-2 concentration favors generation of early memory T cells over effector phenotypes during chimeric antigen receptor T-cell expansion.在嵌合抗原受体T细胞扩增过程中，低白细胞介素-2浓度有利于早期记忆性T细胞而非效应细胞表型的产生。

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Low interleukin-2 concentration favors generation of early memory T cells over effector phenotypes during chimeric antigen receptor T-cell expansion.

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