锰催化的 C-H 功能化反应：涉及意外杂芳基迁移的氢芳基化和烯基化反应。
Manganese-Catalyzed C-H Functionalizations: Hydroarylations and Alkenylations Involving an Unexpected Heteroaryl Shift.
机构信息
Institute of Organic Chemistry, RWTH Aachen, Landoltweg 1, 52074, Aachen, Germany.
Institute of Inorganic Chemistry, RWTH Aachen, Landoltweg 1, 52074, Aachen, Germany.
出版信息
Angew Chem Int Ed Engl. 2017 Aug 7;56(33):9935-9938. doi: 10.1002/anie.201704682. Epub 2017 Jul 17.
A manganese-catalyzed regio- and stereoselective hydroarylation of allenes is reported. The C-H functionalization method provides access to various alkenylated indoles in excellent yields. Moreover, a hydroarylation/cyclization cascade involving an unexpected C-N bond cleavage and aryl shift has been developed, which provides a new synthetic approach to substituted pyrroloindolones.
报道了锰催化的丙二烯的区域和立体选择性氢芳基化反应。C-H 官能化方法可获得各种烯基吲哚，产率优异。此外，还开发了一种涉及意外 C-N 键断裂和芳基迁移的氢芳基化/环化级联反应，为取代的吡咯并吲哚酮提供了一种新的合成方法。
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