Suppr超能文献

英夫利昔单抗治疗小儿溃疡性结肠炎期间的心包炎

Pericarditis during infliximab therapy in paediatric ulcerative colitis.

作者信息

Dipasquale V, Gramaglia S M C, Catena M A, Romano C

机构信息

Unit of Pediatrics, Department of Human Pathology in Adulthood and Childhood "G. Barresi", University of Messina, Messina, Italy.

出版信息

J Clin Pharm Ther. 2018 Feb;43(1):107-109. doi: 10.1111/jcpt.12586. Epub 2017 Jun 23.

Abstract

WHAT IS KNOWN AND STUDY OBJECTIVE

Infliximab is a widely used drug for treating inflammatory bowel disease (IBD). This drug is known to rarely cause pericarditis in adult populations.

CASE SUMMARY

This report details the case of a 14-year-old boy with ulcerative colitis who developed pericarditis after a second infliximab infusion. After discontinuation of therapy, the patient's symptoms were resolved.

WHAT IS NEW AND CONCLUSION

To our knowledge, this is the first reported paediatric case of pericarditis as a possible complication of infliximab therapy in IBD. Among infliximab-related delayed adverse reactions, cardiac complications should be monitored in the paediatric population.

摘要

已知信息与研究目的

英夫利昔单抗是一种广泛用于治疗炎症性肠病(IBD)的药物。已知该药物在成人中很少引起心包炎。

病例摘要

本报告详细介绍了一名14岁溃疡性结肠炎男孩在第二次输注英夫利昔单抗后发生心包炎的病例。停药后,患者症状缓解。

新发现与结论

据我们所知,这是首例报告的英夫利昔单抗治疗IBD可能并发心包炎的儿科病例。在英夫利昔单抗相关的延迟不良反应中,应监测儿科患者的心脏并发症。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验