Fitzpatrick Ryan, Paterson Nicholas R, Belanger Eric C, McCurdy Arleigh, Watterson James
Division of Urology, Department of Surgery, University of Ottawa, The Ottawa Hospital, Ottawa, Ontario, Canada.
Can J Urol. 2017 Jun;24(3):8868-8870.
Amyloidosis is a protein folding disorder characterized by the deposition of fibrillar proteins into solid organs or tissues. Primary localized amyloidosis of the bladder is very rare and can mimic bladder cancer in its presentation with hematuria, lower urinary tract symptoms or a mass on imaging. A case of localized amyloidosis of the bladder in a 48-year-old man with painless gross hematuria and evidence of bladder mass on ultrasound is presented. Amyloidosis is a rare but important non-malignant process of the bladder. We present a review of the literature and suggestions for management of this rare bladder disease.
淀粉样变性是一种蛋白质折叠紊乱疾病，其特征是纤维状蛋白质沉积于实体器官或组织中。膀胱原发性局限性淀粉样变性非常罕见，在表现为血尿、下尿路症状或影像学检查发现肿块时，可能会被误诊为膀胱癌。本文介绍了一例48岁男性膀胱局限性淀粉样变性病例，该患者有无痛性肉眼血尿，超声检查显示膀胱有肿块。淀粉样变性是膀胱罕见但重要的非恶性病变过程。我们对相关文献进行了综述，并提出了针对这种罕见膀胱疾病的管理建议。
