Infectious Diseases Unit, Royal Children's Hospital Melbourne, Parkville, Australia; Department of Paediatrics, The University of Melbourne, Parkville, Australia; Murdoch Children's Research Institute, Parkville, Australia.
Department of Paediatrics, The University of Melbourne, Parkville, Australia; Academic Unit of Clinical & Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton, UK; NIHR Respiratory Biomedical Research Unit, University Hospital Southampton NHS Foundation Trust, Southampton, UK; Global Health Research Institute, University of Southampton, Southampton, UK; Department of Paediatric Infectious Diseases & Immunology, Evelina London Children's Hospital, Guy's and St. Thomas' NHS Foundation Trust, London, UK.
J Infect. 2017 Jun;74 Suppl 1:S136-S142. doi: 10.1016/S0163-4453(17)30204-9.
Recent studies suggest that the incidence of nontuberculous mycobacterial infections in children may be increasing. Nontuberculous mycobacterial lymphadenitis, skin and soft tissue infection, and pulmonary disease each present unique challenges in relation to diagnosis and treatment. In this update, we critically review the recent literature on the epidemiology, clinical features, diagnostic approaches and treatment of nontuberculous mycobacterial disease in children. In addition, we outline key areas warranting further research.
最近的研究表明,儿童中非结核分枝杆菌感染的发病率可能正在上升。非结核分枝杆菌性淋巴结炎、皮肤和软组织感染以及肺部疾病在诊断和治疗方面都各自存在独特的挑战。在本更新中,我们批判性地回顾了最近关于儿童中非结核分枝杆菌病的流行病学、临床特征、诊断方法和治疗的文献。此外,我们还概述了需要进一步研究的关键领域。