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社交技能训练对自闭症谱系障碍儿童和青少年的作用:一项随机对照试验。

Social Skills Training for Children and Adolescents With Autism Spectrum Disorder: A Randomized Controlled Trial.

机构信息

Center of Neurodevelopmental Disorders (KIND), Neuropsychiatry Unit, Karolinska Institutet, Stockholm, and Child and Adolescent Psychiatry, Center for Psychiatry Research, Stockholm County Council, Stockholm.

Karolinska Institutet.

出版信息

J Am Acad Child Adolesc Psychiatry. 2017 Jul;56(7):585-592. doi: 10.1016/j.jaac.2017.05.001. Epub 2017 May 10.

DOI:10.1016/j.jaac.2017.05.001
PMID:28647010
Abstract

OBJECTIVE

Social skills group training (SSGT) for children and adolescents with autism spectrum disorder (ASD) is widely applied, but effectiveness in real-world practice has not yet been properly evaluated. This study sought to bridge this gap.

METHOD

This 12-week pragmatic randomized controlled trial of SSGT compared to standard care alone was conducted at 13 child and adolescent psychiatry outpatient units in Sweden. Twelve sessions of manualized SSGT ("KONTAKT") were delivered by regular clinical staff. Participants (N = 296; 88 females and 208 males) were children (n = 172) and adolescents (n = 124) aged 8 to 17 years with ASD without intellectual disability. The primary outcome was the Social Responsiveness Scale rating by parents and blinded teachers. Secondary outcomes included parent- and teacher-rated adaptive behaviors, trainer-rated global functioning and clinical severity, and self-reported child and caregiver stress. Assessments were made at baseline, posttreatment, and 3-month follow-up. Moderator analyses were conducted for age and gender.

RESULTS

Significant treatment effects on the primary outcome were limited to parent ratings for the adolescent subgroup (posttreatment: -8.3; 95% CI = -14.2 to -1.9; p = .012, effect size [ES] = 0.32; follow-up: -8.6; 95% CI = -15.4 to -1.8; p = .015, ES = 0.33) and females (posttreatment: -8.9; 95% CI = -16.2 to -1.6; p = .019, ES = 0.40). Secondary outcomes indicated moderate effects on adaptive functioning and clinical severity.

CONCLUSION

SSGT for children and adolescents with ASD in regular mental health services is feasible and safe. However, the modest and inconsistent effects underscore the importance of continued efforts to improve SSGT beyond current standards.

CLINICAL TRIAL REGISTRATION INFORMATION

Social Skills Group Training ("KONTAKT") for Children and Adolescent With High-functioning Autism Spectrum Disorders; https://clinicaltrials.gov/; NCT01854346.

摘要

目的

社交技能团体训练(SSGT)广泛应用于自闭症谱系障碍(ASD)儿童和青少年,但在实际应用中的效果尚未得到适当评估。本研究旨在弥补这一空白。

方法

本研究是一项在瑞典 13 个儿童和青少年精神病学门诊单位进行的为期 12 周的实用随机对照试验,将 SSGT 与单纯标准护理进行比较。由常规临床工作人员提供 12 节标准化 SSGT(“KONTAKT”)。参与者(N=296;88 名女性和 208 名男性)为 8 至 17 岁的自闭症儿童(n=172)和青少年(n=124),无智力障碍。主要结局指标为父母和盲法教师评定的社交反应量表评分。次要结局指标包括父母和教师评定的适应行为、培训师评定的整体功能和临床严重程度以及儿童和照顾者自我报告的压力。评估在基线、治疗后和 3 个月随访时进行。进行了年龄和性别调节分析。

结果

主要结局的治疗效果仅限于青少年亚组的父母评分(治疗后:-8.3;95%CI=-14.2 至-1.9;p=0.012,效应量[ES]=0.32;随访:-8.6;95%CI=-15.4 至-1.8;p=0.015,ES=0.33)和女性(治疗后:-8.9;95%CI=-16.2 至-1.6;p=0.019,ES=0.40)。次要结局表明适应功能和临床严重程度有中等影响。

结论

在常规心理健康服务中,对自闭症谱系障碍儿童和青少年进行社交技能团体训练是可行和安全的。然而,适度和不一致的效果强调了在现有标准之外进一步努力改进社交技能团体训练的重要性。

临床试验注册信息

社交技能团体训练(“KONTAKT”)用于高功能自闭症谱系障碍的儿童和青少年;https://clinicaltrials.gov/;NCT01854346。

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