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使用乙烯-乙烯醇共聚物(Onyx)栓塞卵巢静脉治疗盆腔淤血综合征。

Embolization of ovarian vein for pelvic congestion syndrome with ethylene vinyl alcohol copolymer (Onyx).

机构信息

Department of Medical Imaging, hôpital de la Timone, 264, rue Saint-Pierre, 13005 Marseille, France.

Department of Medical Imaging, hôpital de la Timone, 264, rue Saint-Pierre, 13005 Marseille, France.

出版信息

Diagn Interv Imaging. 2017 Dec;98(12):843-848. doi: 10.1016/j.diii.2017.05.011. Epub 2017 Jun 22.

DOI:10.1016/j.diii.2017.05.011
PMID:28647478
Abstract

PURPOSE

To evaluate the safety and efficacy of pelvic embolization using ethylene vinyl alcohol copolymer (Onyx) for pelvic congestion syndrome.

MATERIAL AND METHODS

Between March 2012 to September 2016, 17 women (mean age, 44.7± 12.2 (SD) years; range: 34-71years) presenting with pelvic congestion syndrome were evaluated for transvenous embolization with Onyx. Pelvic congestion syndrome was initially diagnosed by clinical examination and the results of transvaginal Doppler ultrasound and further confirmed by pelvic venography. Primary and secondary clinical efficacy was defined respectively by the resolution of the symptoms after embolization and at the end of the follow-up, irrespective to the number of embolization procedures.

RESULTS

Technical efficacy of embolization was 100% with no significant complications during and after embolization. After a mean follow-up time of 24.2 months (range: 6-69months) a primary and secondary clinical efficacy of 76.4% (13/17 women) and 94.1% (16/17 women) respectively were observed. Four women (23.5%) underwent a second embolization procedure with one woman requiring a third embolization procedure. These additional embolization procedures were associated with direct puncture of vulvar varices for sclerotherapy in two women. Five women (29%) had recurrent symptoms 21 months post-treatment (7-42months).

CONCLUSION

Pelvic embolization using ethylene vinyl alcohol copolymer (Onyx) has a favorable clinical success for pelvic congestion syndrome.

摘要

目的

评估使用乙烯-乙烯醇共聚物(Onyx)进行盆腔栓塞治疗盆腔淤血综合征的安全性和疗效。

材料和方法

2012 年 3 月至 2016 年 9 月,17 例(平均年龄 44.7±12.2(SD)岁;范围:34-71 岁)患有盆腔淤血综合征的女性接受了 Onyx 经静脉栓塞治疗。盆腔淤血综合征最初通过临床检查、经阴道多普勒超声检查结果以及盆腔静脉造影进一步诊断。栓塞治疗后的症状缓解和随访结束时的症状缓解分别定义为原发性和继发性临床疗效,而与栓塞治疗的次数无关。

结果

栓塞治疗的技术成功率为 100%,栓塞治疗过程中和治疗后无明显并发症。平均随访 24.2 个月(范围:6-69 个月)后,观察到原发性和继发性临床疗效分别为 76.4%(17 例女性中的 13 例)和 94.1%(17 例女性中的 16 例)。4 例女性(23.5%)接受了第二次栓塞治疗,其中 1 例女性需要进行第三次栓塞治疗。这些额外的栓塞治疗与 2 例女性外阴静脉曲张的直接穿刺硬化治疗有关。5 例女性(29%)在治疗后 21 个月(7-42 个月)出现复发症状。

结论

使用乙烯-乙烯醇共聚物(Onyx)进行盆腔栓塞治疗盆腔淤血综合征具有良好的临床疗效。

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