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盆腔静脉疾病患者中弹簧圈栓塞联合硬化治疗与N-丁基-2-氰基丙烯酸酯栓塞术的比较:一项单中心回顾性研究

Coil occlusion combined with sclerotherapy versus N-butyl-2-cyanoacrylate embolization in patients with pelvic venous disorders: A single-center retrospective study.

作者信息

Zaghloul Hossam, Nasser Mahmoud, El-Mawgoud Hisham Abd, Ghoneim Baker, Ali Mohammed

机构信息

Vascular and Endovascular Surgery, Faculty of Medicine, Cairo University, Cairo, Egypt.

Vascular and Endovascular Surgery, Faculty of Medicine, Cairo University, Cairo, Egypt; Vascular and Endovascular Department, Sheffield Teaching Hospitals NHS Trust, Sheffield, UK.

出版信息

J Vasc Surg Venous Lymphat Disord. 2025 Jul;13(4):102241. doi: 10.1016/j.jvsv.2025.102241. Epub 2025 Mar 28.

Abstract

BACKGROUND

Pelvic venous disorder (PeVD) is increasingly diagnosed with different modalities of treatment.

METHODS

This is a retrospective study in which we compared using metallic coil combined with sclerosant foam and N-butyl-2-cyanoacrylate in female patients with PeVD in terms of clinical and technical success as well as safety. Adult patients with symptoms suggestive of primary PeVD and confirmed with Doppler ultrasound examination and/or venography were eligible for the study. Secondary PeVD and lost follow-up were excluded.

RESULTS

This study included 167 patients who were treated with coil and sclerotherapy (n = 87; group I) or N-butyl-2-cyanoacrylate (n = 80; group II) embolization. Immediate postoperative veins' closure was achieved in all patients in the two groups. At the 6-month follow-up, there was a statistically significantly higher occlusion rate in group I (100% compared with 93.8% in group II, P = .018) with five new cases of recanalization. The 6-month visual analog scale score was lower in group I (median of 1 and mean of 1.14 ± 0.904) than group II (median of 2 and mean of 1.7 ± 1.32), with a statistically significant difference (P = .005).

CONCLUSIONS

The study emphasizes the potential advantages of the sclerosant foam and metallic coil combination in achieving favorable outcomes for patients with PeVD.

摘要

背景

盆腔静脉疾病(PeVD)越来越多地通过不同的治疗方式进行诊断。

方法

这是一项回顾性研究,我们比较了在患有PeVD的女性患者中使用金属线圈联合硬化剂泡沫和N-丁基-2-氰基丙烯酸酯在临床和技术成功率以及安全性方面的差异。有原发性PeVD症状并经多普勒超声检查和/或静脉造影确诊的成年患者符合本研究条件。继发性PeVD和失访患者被排除。

结果

本研究纳入了167例接受线圈和硬化治疗(n = 87;第一组)或N-丁基-2-氰基丙烯酸酯栓塞治疗(n = 80;第二组)的患者。两组所有患者术后均立即实现静脉闭合。在6个月的随访中,第一组的闭塞率在统计学上显著更高(100%,而第二组为93.8%,P = 0.018),有5例再通新病例。第一组的6个月视觉模拟量表评分(中位数为1,平均值为1.14±0.904)低于第二组(中位数为2,平均值为1.7±1.32),差异有统计学意义(P = 0.005)。

结论

该研究强调了硬化剂泡沫和金属线圈联合使用在为PeVD患者取得良好治疗效果方面的潜在优势。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7336/12144509/cbdbd12c72d9/gr1.jpg

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