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五种烟草终结策略对未来吸烟流行率、人口健康和卫生系统成本的影响:为烟草终结提供信息的两项建模研究。

Impact of five tobacco endgame strategies on future smoking prevalence, population health and health system costs: two modelling studies to inform the tobacco endgame.

机构信息

Burden of Disease Epidemiology, Equity and Cost Effectiveness Programme (BODE3), University of Otago, Wellington, New Zealand.

Centre for Health Policy, Melbourne School of Population and Global Health, University of Melbourne, Melbourne, Victoria, Australia.

出版信息

Tob Control. 2018 May;27(3):278-286. doi: 10.1136/tobaccocontrol-2016-053585. Epub 2017 Jun 24.

Abstract

OBJECTIVE

There is growing international interest in advancing 'the tobacco endgame'. We use New Zealand (Smokefree goal for 2025) as a case study to model the impacts on smoking prevalence (SP), health gains (quality-adjusted life-years (QALYs)) and cost savings of (1) 10% annual tobacco tax increases, (2) a tobacco-free generation (TFG), (3) a substantial outlet reduction strategy, (4) a sinking lid on tobacco supply and (5) a combination of 1, 2 and 3.

METHODS

Two models were used: (1) a dynamic population forecasting model for SP and (2) a closed cohort (population alive in 2011) multistate life table model (including 16 tobacco-related diseases) for health gains and costs.

RESULTS

All selected tobacco endgame strategies were associated with reductions in SP by 2025, down from 34.7%/14.1% for Māori (indigenous population)/non-Māori in 2011 to 16.0%/6.8% for tax increases; 11.2%/5.6% for the TFG; 17.8%/7.3% for the outlet reduction; 0% for the sinking lid; and 9.3%/4.8% for the combined strategy. Major health gains accrued over the remainder of the 2011 population's lives ranging from 28 900 QALYs (95% Uncertainty Interval (UI)): 16 500 to 48 200; outlet reduction) to 282 000 QALYs (95%UI: 189 000 to 405 000; sinking lid) compared with business-as-usual (3% discounting). The timing of health gain and cost savings greatly differed for the various strategies (with accumulated health gain peaking in 2040 for the sinking lid and 2070 for the TFG).

CONCLUSIONS

Implementing endgame strategies is needed to achieve tobacco endgame targets and reduce inequalities in smoking. Given such strategies are new, modelling studies provide provisional information on what approaches may be best.

摘要

目的

推进“烟草终结”在国际上受到越来越多的关注。我们以新西兰(2025 年无烟目标)为例,构建模型以评估以下五种策略对吸烟流行率(SP)、健康收益(质量调整生命年(QALYs))和成本节约的影响:(1)每年 10%的烟草税提高,(2)无烟草世代(TFG),(3)大量减少烟草销售点,(4)烟草供应封顶,(5)策略 1、2 和 3 的结合。

方法

使用了两种模型:(1)用于 SP 预测的动态人口预测模型,(2)包括 16 种与烟草相关疾病的封闭队列(2011 年存活人口)多状态生命表模型。

结果

所有选定的烟草终结策略都与 2025 年 SP 降低相关,2011 年毛利人(原住民)/非毛利人(34.7%/14.1%)下降至 2025 年的 16.0%/6.8%,其中税收增加策略为 16.0%/6.8%,TFG 策略为 11.2%/5.6%,销售点减少策略为 17.8%/7.3%,供应封顶策略为 0%,综合策略为 9.3%/4.8%。在 2011 年人口的剩余寿命中,将获得重大健康收益,范围从 28900QALYs(95%不确定性区间(UI):16500 至 48200;销售点减少策略)到 282000QALYs(95%UI:189000 至 405000;供应封顶策略),与现状相比(3%贴现)。各种策略的健康收益和成本节约的时间点差异很大(供应封顶策略的累计健康收益峰值出现在 2040 年,TFG 策略的峰值出现在 2070 年)。

结论

需要实施终结策略来实现烟草终结目标并减少吸烟方面的不平等。鉴于这些策略是新的,建模研究提供了关于哪些方法可能是最佳方法的初步信息。

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