Josiassen Michael, Larsen Christian Grønhøj, Lajer Christel Bræmer, Charabi Birgitte, Buchwald Christian von
Ugeskr Laeger. 2017 Jun 19;179(25).
The prevalence of oropharyngeal cancer is increasing in the Western world, and human papillomavirus (HPV) is believed to play a role in this development. Patients with HPV-positive oropharyngeal cancer differ significantly from patients with HPV-negative cancer. They may present solely with a small cervical metastasis and thus undergo an extensive diagnostic workup. Treatment modalities include radiotherapy often in combination with chemotherapy. However, new surgical advances are now possible. In this review we discuss the changing epidemiology, virology, symptomatology and different treatment modalities.
在西方世界，口咽癌的患病率正在上升，人们认为人乳头瘤病毒（HPV）在这一发展过程中发挥了作用。HPV阳性口咽癌患者与HPV阴性口咽癌患者有显著差异。他们可能仅表现为小的颈部转移，因此需要进行广泛的诊断性检查。治疗方式包括通常与化疗联合的放疗。然而，现在新的手术进展成为可能。在本综述中，我们讨论了不断变化的流行病学、病毒学、症状学以及不同的治疗方式。
