Ohnaka Keizo
Department of Geriatric Medicine, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.
Clin Calcium. 2017;27(7):947-954.
The decline in sex hormones along with aging is suggested to be involved in age-associated diseases such as cardiovascular diseases, osteoporosis, and dementia. The decrease of estrogen level after menopause is related to osteoporosis in addition to climacteric disturbance in women, while that of testosterone to sarcopenia, osteoporosis and late-onset hypogonadism in men. New treatment strategy is expected for targeting age-associated diseases against the decreased level of sex hormones.
随着年龄增长，性激素水平下降被认为与心血管疾病、骨质疏松症和痴呆症等与年龄相关的疾病有关。绝经后雌激素水平的下降除了导致女性更年期紊乱外，还与骨质疏松症有关，而睾酮水平的下降则与男性肌肉减少症、骨质疏松症和迟发性性腺功能减退有关。针对因性激素水平降低而引发的与年龄相关的疾病，有望出现新的治疗策略。
