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在蛋壳形成不同阶段给予滴滴涕后,鸭蛋壳腺黏膜亚细胞组分中钙代谢与ATP酶活性之间的关系。

Relation between Ca metabolism and ATPase activities in the subcellular fractions from duck eggshell gland mucosa after DDE administration during different stages of eggshell formation.

作者信息

Lundholm C E

出版信息

Comp Biochem Physiol C Comp Pharmacol Toxicol. 1985;82(1):1-16. doi: 10.1016/0742-8413(85)90202-6.

Abstract

The ATP-dependent Ca2+ uptake by and the Ca2+-Mg2+-activated ATPase activity in the subcellular fractions from the eggshell gland of two varieties of ducks, Indian Runner ducks (IRD) and the cross-breed of Swedish and Rouen ducks (SRD), showed functional changes during eggshell formation in relation to the values in the resting state. DDE inhibited the Ca2+ uptake (Ca) but increased the Ca2+-Mg2+-ATPase activity (P) of fractions from active but not of those from resting glands. DDE reduced the Ca/P ratio of several fractions from active glands. DDE inhibited the functional increase in Ca2+-Mg2+-ATPase in the IRD homogenate, however. The effect of DDE on the eggshell index of mature eggshell was greater in IRD than in SRD, the reason for this being that the effect was exerted during a shorter time period in the latter variety.

摘要

两种鸭,即印度跑鸭(IRD)和瑞典鸭与鲁昂鸭的杂交品种(SRD),其蛋壳腺亚细胞组分中的ATP依赖性Ca²⁺摄取以及Ca²⁺-Mg²⁺激活的ATP酶活性,在蛋壳形成过程中相对于静止状态的值表现出功能变化。滴滴涕抑制Ca²⁺摄取(Ca),但增加了来自活跃腺体而非静止腺体组分的Ca²⁺-Mg²⁺-ATP酶活性(P)。滴滴涕降低了来自活跃腺体的几个组分的Ca/P比值。然而,滴滴涕抑制了IRD匀浆中Ca²⁺-Mg²⁺-ATP酶的功能增加。滴滴涕对成熟蛋壳蛋壳指数的影响在IRD中比在SRD中更大,其原因是在后者品种中该影响在更短的时间段内发挥作用。

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Comparison of p-p'-DDE and o-p'-DDE on eggshell thickness and Ca binding activity of shell gland in ducks.
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