滴滴涕对鸭蛋壳腺及其亚细胞组分钙代谢的影响；与功能阶段的关系。
Effect of DDE on the Ca metabolism of the duck eggshell gland and its subcellular fractions; relation to the functional stage.
作者信息
Lundholm C E
出版信息
Comp Biochem Physiol C Comp Pharmacol Toxicol. 1984;78(1):5-12. doi: 10.1016/0742-8413(84)90039-2.
Administration of DDE to Indian Runner ducks (Anas platyrhynchos var.) reduced the eggshell index by 28% and the calcium content of the secreted fluid in the shell gland by 25%. DDE inhibited the functional decrease of the calcium content of the gland cells that occurred during eggshell formation. DDE reduced the functional increase in the ATP-dependent binding of Ca2+ to a microsomal subfraction FIII prepared from Ca-secreting glands forming an eggshell. In subfraction FI the Ca2+ binding was decreased by DDE even when the gland contained a mature shell. FIII probably contained calcium-secreting granules, whereas FI contained plasma membrane fragments of the gland cells.
给印度跑鸭（Anas platyrhynchos var.）施用滴滴涕（DDE）会使蛋壳指数降低28%，使壳腺分泌液中的钙含量降低25%。滴滴涕抑制了蛋壳形成过程中腺细胞钙含量的功能性降低。滴滴涕降低了由形成蛋壳的钙分泌腺制备的微粒体亚组分FIII中，ATP依赖的Ca2+结合的功能性增加。在亚组分FI中，即使腺体含有成熟的蛋壳，滴滴涕也会降低Ca2+结合。FIII可能含有钙分泌颗粒，而FI含有腺细胞的质膜碎片。
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