Miyakawa I, Yasuda H, Taniyama K, Mori N, Uehara Y, Sumiyoshi A
Int J Gynaecol Obstet. 1985 Jun;23(3):213-6. doi: 10.1016/0020-7292(85)90107-9.
A 46-year-old woman, who had very interesting tumor of the vagina microscopically, was presented. The removed tumor (40 g) in the upper lateral wall of the vagina was composed of two nodules. The cut surface of one nodule (20 g) was separated into two parts and they were diagnosed as necrosis and borderline case of leiomyomata microscopically. The other nodule (20 g) was diagnosed as leiomyosarcoma with interlacing bundles of spindle-shaped cells with large hyperchromatic, irregularly shaped nuclei and abundant mutases. These bindings suggest a possibility that leiomyoma of the vagina may undergo malignant change to become leiomyosarcoma.
报告了一名46岁女性，其阴道肿瘤在显微镜下表现非常有趣。切除的位于阴道上侧壁的肿瘤（40克）由两个结节组成。其中一个结节（20克）的切面分为两部分，显微镜下诊断为坏死和平滑肌瘤的交界性病例。另一个结节（20克）诊断为平滑肌肉瘤，有交织成束的梭形细胞，细胞核大、深染、形状不规则，且有丰富的核仁。这些表现提示阴道平滑肌瘤可能发生恶性变成为平滑肌肉瘤。
