Balakrishnan Deepthy, Jena Saubhagya Kumar, Mishra Pritinanda
Department of OBG, AIIMS, Bhubaneswar, Odisha, India.
Department of Pathology and Laboratory Medicine, AIIMS, Bhubaneswar, Odisha, India.
J Midlife Health. 2024 Apr-Jun;15(2):125-127. doi: 10.4103/jmh.jmh_70_24. Epub 2024 Jul 5.
Leiomyosarcomas (LMS) arise from smooth muscle cells with more predilection to the uterus, abdomen, retroperitoneum, and blood vessels. LMS of vagina is very rare and usually presents in the early stage as an asymptomatic mobile mass with no clinical features of malignancy and gives the appearance of a benign lesion which can easily be mistaken for a Bartholin's cyst or a vaginal fibroid. The chances of metastasis in LMS are high with poor survival rates. Histopathology confirms the diagnosis and treatment still remains controversial due to less data on this rare malignancy. Even though there is no evidence that leiomyoma can transform into LMS, benign-looking vaginal fibroids need to be resected to avoid misdiagnosis of LMS. We present a case of vaginal LMS which was mistaken to be Bartholin's cyst due to the lack of knowledge of this aggressive tumor and further management.
平滑肌肉瘤(LMS)起源于平滑肌细胞,更易发生于子宫、腹部、腹膜后和血管。阴道平滑肌肉瘤非常罕见,早期通常表现为无症状的可移动肿块,无恶性肿瘤的临床特征,外观似良性病变,容易被误诊为巴氏腺囊肿或阴道纤维瘤。平滑肌肉瘤转移的可能性高,生存率低。组织病理学可确诊,但由于关于这种罕见恶性肿瘤的数据较少,其治疗仍存在争议。尽管没有证据表明平滑肌瘤可转变为平滑肌肉瘤,但外观良性的阴道纤维瘤仍需切除,以避免误诊为平滑肌肉瘤。我们报告一例阴道平滑肌肉瘤病例,由于对这种侵袭性肿瘤缺乏了解及其后续处理,该病例最初被误诊为巴氏腺囊肿。