Department of Maternal and Child Health, School of Public Health, Sun Yat-sen University.
Department of Clinical Laboratory, the First Affiliated Hospital of Sun Yat-sen University.
J Atheroscler Thromb. 2018 Jan 1;25(1):81-89. doi: 10.5551/jat.38570. Epub 2017 Jun 23.
Excessive consumption of sugar-sweetened beverages (SSBs) may increase the prevalence of obesity and other metabolic risk factors. However, data regarding the relationship between SSB consumption and metabolic risk factors are insufficient in Chinese children. Hence, we aimed to explore the association between SSB consumption and cardio-metabolic risk factors in children aged 7-18 years living in South China.
A cross-sectional study was conducted in a total of 2,032 children aged 7-18 years were enrolled, including 1,013 boys and 1,019 girls. Based on a multistage cluster sampling, five elementary and four secondary schools in Guangzhou, China were included. Fasting blood glucose levels, lipid profiles, and anthropometric characteristics were evaluated. Information on demography, dietary, and physical activities were self-reported.
Overall, 34.7% participants were non-drinkers and 21.6% consumed more than 120 mL/day SSB. The body mass index (19.43±0.18 kg/m) and triglyceride concentration (0.96±0.03 mmol/L) were higher and high-density lipoprotein concentration (1.32±0.31 mmol/L) was lower in consumers than in non-consumers (all P<0.001). Furthermore, in contrast to non-consumers, the adjusted odds ratio of SSB consumption more than 120 mL/day was 2.08 (95% CI: 1.21-3.54) for obesity, 1.83 (95% CI: 1.25-2.69) for abdominal obesity, and 1.70 (95% CI: 1.02-3.06) for hypertriglyceridemia in consumers.
A positive association between SSB consumption and the risks of obesity and hypertriglyceridemia was observed in children living in South China, which suggests that high SSB consumption enhances the risk of cardio-metabolic risk factors and the consequent cardio-metabolic diseases.
过量摄入含糖饮料(SSB)可能会增加肥胖和其他代谢危险因素的流行率。然而,关于 SSB 摄入与代谢危险因素之间关系的数据在中国儿童中还不够充分。因此,我们旨在探讨中国南方 7-18 岁儿童 SSB 摄入与心血管代谢危险因素之间的关系。
本研究共纳入 2032 名 7-18 岁的儿童,包括 1013 名男孩和 1019 名女孩。采用多阶段聚类抽样的方法,纳入中国广州的五所小学和四所中学。评估了空腹血糖水平、血脂谱和人体测量特征。通过自报的方式获取了有关人口统计学、饮食和身体活动的信息。
总体而言,34.7%的参与者为非饮者,21.6%的参与者每天饮用超过 120ml 的 SSB。与非饮者相比,饮者的体重指数(19.43±0.18kg/m)和三酰甘油浓度(0.96±0.03mmol/L)更高,高密度脂蛋白浓度(1.32±0.31mmol/L)更低(均 P<0.001)。此外,与非饮者相比,每天饮用超过 120ml 的 SSB 与肥胖(调整后的优势比[OR]:2.08,95%置信区间[CI]:1.21-3.54)、腹型肥胖(OR:1.83,95%CI:1.25-2.69)和高三酰甘油血症(OR:1.70,95%CI:1.02-3.06)的风险呈正相关。
在中国南方地区,SSB 摄入与肥胖和高三酰甘油血症的风险呈正相关,这表明大量摄入 SSB 会增加心血管代谢危险因素的风险,进而导致心血管代谢疾病。