Ye Peiyu, Yan Yinkun, Ding Wenqing, Dong Hongbo, Liu Qin, Huang Guimin, Mi Jie
Department of Epidemiology, Capital Institute of Pediatrics, Beijing 100020, China.
Department of Epidemiology, Capital Institute of Pediatrics, Beijing 100020, China; School of Public Health, Ningxia Medical University.
Zhonghua Liu Xing Bing Xue Za Zhi. 2015 Aug;36(8):884-8.
To evaluate the prevalence of metabolic syndrome (MS) in Chinese children and adolescents to provide scientific basis for early prevention of MS in the related populations.
Studies on CNKI, Wanfangdata, VIP and PubMed databases on related prevalence of metabolic syndrome in Chinese children and adolescents between 2004-2014 were searched. Quality of literatures was evaluated according to the cross-sectional study standard in Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) statement. Stata 12.0 software was used to estimate the prevalence of MS, as well as on gender, weight and other factors to make subgroup analysis. According to funnel plot and Egger assess publication bias, sensitivity analysis performed by excluding the impact of any article was generated by the combined effect of the value of literature.
This study included 19 papers from the literature (5 in English, 14 in Chinese). According to International Diabetes Federation (IDF), National Cholesterol Education Program III (NCEP III) and The definition and prevention recommends of metabolic syndrome in Chinese children and adolescents (CHN2012), the prevalence rates of MS in Chinese children were seen as 1.8%, 2.6% and 2.0%. According to IDF, the prevalence rates of MS appeared 2.9% in boys and 1.8% in girls, 0.2% in children with normal weight, 4.7% in overweight and 17.3% in obesity. Both the results from NCEPIII and CHN2012 showed that the prevalence rates of MS as boys > girls, obesity > overweight > normal weight.
Prevalence of MS in Chinese children and adolescents showed a general trend. Data under different standards showed different prevalence rates. Obesity appeared an important risk factor of MS, suggesting that in order to control obesity in children, attention should be paid to identifying and carrying out effective interventions on children under overweight or obesity.
评估中国儿童和青少年代谢综合征（MS）的患病率，为相关人群MS的早期预防提供科学依据。
检索中国知网、万方数据、维普数据库以及PubMed数据库中2004 - 2014年有关中国儿童和青少年代谢综合征患病率的研究。根据《加强流行病学观察性研究报告规范》（STROBE）声明中的横断面研究标准对文献质量进行评估。使用Stata 12.0软件估计MS的患病率，并按性别、体重等因素进行亚组分析。根据漏斗图和Egger检验评估发表偏倚，通过排除任何一篇文章的影响进行敏感性分析，由文献合并效应值产生。
本研究纳入文献19篇（英文5篇，中文14篇）。根据国际糖尿病联盟（IDF）、美国国家胆固醇教育计划第三次报告（NCEP III）以及《中国儿童青少年代谢综合征定义和防治建议》（CHN2012），中国儿童MS患病率分别为1.8%、2.6%和2.0%。按照IDF标准，MS患病率男性为2.9%，女性为1.8%；体重正常儿童为0.2%，超重儿童为4.7%，肥胖儿童为17.3%。NCEPIII和CHN2012的结果均显示，MS患病率男性>女性，肥胖>超重>体重正常。
中国儿童和青少年MS患病率呈总体趋势。不同标准下的数据显示出不同的患病率。肥胖是MS的重要危险因素，提示为控制儿童肥胖，应重视对超重或肥胖儿童进行识别并开展有效干预。
