Demirkan Serkan, Gündüz Özgür, Sayan Cemile Dayangan
Department of Dermatology.
Department of Gynecology and Obstetric, Kirkkale University, Kirikkale, Turkey.
Dermatol Reports. 2017 May 16;9(1):7027. doi: 10.4081/dr.2017.7027. eCollection 2017 Mar 13.
Melasma is an acquired diffuse hypermelanosis characterized by localized, symmetrical, irregular, light-to-dark brown maculae occurring in sun-exposed areas of skin. The aim of this retrospective study was to determine demographics of patients, analysis of etiologic factors, clinical features, efficacy and side effects of available topical treatments due to high incidence of melasma patients. In this study melasma patients in Birecik State Hospital were investigated retrospectively. Between January 2014 and October 2015, 1008 patients had diagnosis of melasma in 49,809 applications of 24,603 different patients who admitted to Dermatology Outpatient Clinics. Of the 1008 patients, 263 had completed 3-month treatment period. These patients did not receive treatment in June, July, August and September. All melasma patients were rural and dealing with agriculture. There was no significant difference between female and male patients in terms of age. Of the 253 female melasma patients, only 2 of them had not child and none of them were using hormone drug. Of the 263 patients with melasma, Fitzpatrick skin type was 3 in 79 (30%) patients, 4 in 184 (70%) patients. Şanliurfa city showed higher fertility rate, sun exposure, and skin type than Turkey as a whole. These predisposing factors may explain higher melasma occurrence in Şanliurfa. Patient information about preventive measures and treatment play important role in treatment of cosmetic condition. The most important measure seems to advise patients about sun-protection especially during pregnancy.
黄褐斑是一种后天性弥漫性色素沉着过度,其特征为在皮肤暴露于阳光的部位出现局限性、对称性、不规则的浅褐色至深褐色斑疹。由于黄褐斑患者发病率较高,本回顾性研究的目的是确定患者的人口统计学特征、分析病因、临床特征、现有局部治疗的疗效和副作用。在本研究中,对比雷吉克州立医院的黄褐斑患者进行了回顾性调查。在2014年1月至2015年10月期间,在皮肤科门诊就诊的24603名不同患者的49809次就诊中,有1008名患者被诊断为黄褐斑。在这1008名患者中,263名完成了3个月的治疗期。这些患者在6月、7月、8月和9月未接受治疗。所有黄褐斑患者均来自农村,从事农业。女性和男性患者在年龄方面无显著差异。在253名女性黄褐斑患者中,只有2名没有孩子,且她们均未使用激素药物。在263名黄褐斑患者中,79名(30%)患者的菲茨帕特里克皮肤类型为3型,184名(70%)患者为4型。与土耳其整体情况相比,Şanliurfa市的生育率、阳光照射和皮肤类型更高。这些诱发因素可能解释了Şanliurfa市黄褐斑发病率较高的原因。患者关于预防措施和治疗的信息在美容疾病的治疗中起着重要作用。最重要的措施似乎是建议患者特别是在怀孕期间进行防晒。